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Löfgren syndrome is a type of acute sarcoidosis, [1] an inflammatory disorder characterized by swollen lymph nodes in the chest, tender red nodules on the shins, fever and arthritis. [2] It is more common in women than men, and is more frequent in those of Scandinavian , Irish , African and Puerto Rican heritage.
In 2015, pulmonary sarcoidosis and interstitial lung disease affected 1.9 million people globally and they resulted in 122,000 deaths. [10] [11] It is most common in Scandinavians, but occurs in all parts of the world. [14] In the United States, risk is greater among black people as opposed to white people. [14]
0.65%: −16.6 Myocarditis: 0.6: ... Interstitial lung disease and pulmonary sarcoidosis: 1.9: ... A study suggests the global "mean loss of life expectancy" ...
It is a type of interstitial lung disease. [3] People often benefit from pulmonary rehabilitation and supplemental oxygen. [1] Certain medications like pirfenidone or nintedanib may slow the progression of the disease. [2] Lung transplantation may also be an option. [1] About 5 million people are affected globally. [8]
Restrictive lung diseases are a category of extrapulmonary, pleural, or parenchymal respiratory diseases that restrict lung expansion, [2] resulting in a decreased lung volume, an increased work of breathing, and inadequate ventilation and/or oxygenation. Pulmonary function test demonstrates a decrease in the forced vital capacity.
In the United States, sarcoidosis has a prevalence of approximately 10 cases per 100,000 whites and 36 cases per 100,000 blacks. [4] Heerfordt syndrome is present in 4.1 to 5.6% of those with sarcoidosis.
Children with Hurler syndrome often die before age 10 from obstructive airway disease, respiratory infections, and cardiac complications. MPS I S, Scheie syndrome , is the mildest form of MPS I. Symptoms generally begin to appear after age 5, with diagnosis most commonly made after age 10.
A British study from 2008 found a median estimated life expectancy of 8.7 years for patients with Hurler syndrome. In comparison, the median life expectancy for all forms of MPS type I was 11.6 years. Patients who received successful bone marrow transplants had a 2-year survival rate of 68% and a 10-year survival rate of 64%. Patients who did ...