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Cevimeline is used in the treatment of xerostomia (dry mouth) [1] [2] and Sjögren's syndrome. [1] It increases the production of saliva. [2] Side effects.
Treatment is directed at managing the person's symptoms. [4] For dry eyes, artificial tears; medications to reduce inflammation; punctal plugs or other surgery to shut the tear ducts may be tried. [4] For a dry mouth, chewing gum (preferably sugar-free); sipping water; or a saliva substitute may be used. [4]
Xerostomia is the subjective sensation of dry mouth, which is often (but not always) associated with hypofunction of the salivary glands. [3] The term is derived from the Greek words ξηρός (xeros) meaning "dry" and στόμα (stoma) meaning "mouth". [4] [5] A drug or substance that increases the rate of salivary flow is termed a sialogogue.
By mouth it is used for dry mouth as a result of Sjögren syndrome or radiation therapy. [9] Common side effects of the eye drops include irritation of the eye, increased tearing, headache, and blurry vision. [1] Other side effects include allergic reactions and retinal detachment. [1] Use is generally not recommended during pregnancy. [10]
A sialogogue (also spelled sialagogue, ptysmagogue or ptyalagogue) is a substance, especially a medication, that increases the flow rate of saliva. [1] The definition focuses on substances that promote production or secretion of saliva (proximal causation) rather than any food that is mouthwatering (distal causation that triggers proximal causation).
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