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Huntington's disease (HD), also known as Huntington's chorea, is an incurable neurodegenerative disease [7] that is mostly inherited. [8] The earliest symptoms are often subtle problems with mood or mental/psychiatric abilities. [9][1] A general lack of coordination and an unsteady gait often follow. [2] It is also a basal ganglia disease ...
Hyperkinesia, more specifically chorea, is the hallmark symptom of Huntington's disease, formerly referred to as Huntington's chorea. Appropriately, chorea is derived from the Greek word, khoros, meaning "dance." The extent of the hyperkinesia exhibited in the disease can vary from solely the little finger to the entire body, resembling ...
Chorea. Chorea (or choreia, occasionally) is an abnormal involuntary movement disorder, characterized by quick movements of the hands or feet. It is one of a group of neurological disorders called dyskinesias. The term chorea is derived from the Ancient Greek: χορεία ("dance"; see choreia), as the movements of the body is comparable to ...
Sydenham's chorea, also known as rheumatic chorea, is a disorder characterized by rapid, uncoordinated jerking movements primarily affecting the face, hands and feet. [ 1 ] Sydenham's chorea is an autoimmune disease that results from childhood infection with Group A beta- haemolytic Streptococcus. It is reported to occur in 20–30% of people ...
In the 1967 film Valley of the Dolls, Tony Polar, the singer married to Jennifer North, has Huntington's Chorea.; Arlo Guthrie's 1969 film Alice's Restaurant, which depicts Guthrie's father Woody suffering from what was then called "Huntington's Chorea", and features numerous mentions of the condition by the younger Guthrie to his peers and the draft board's medical staff.
George Huntington (April 9, 1850 – March 3, 1916) was an American physician who contributed a classic clinical description of the disease that bears his name— Huntington's disease. [1] Huntington described this condition in the first of only two scientific papers he ever wrote. He wrote this paper when he was 22, a year after receiving his ...
Nancy Wexler. Nancy Wexler (born 19 July 1945) [1] FRCP is an American geneticist and the Higgins Professor of Neuropsychology in the Departments of Neurology and Psychiatry of the Columbia University College of Physicians and Surgeons, best known for her involvement in the discovery of the location of the gene that causes Huntington's disease.
Sydenham's chorea is a disorder characterized by rapid, uncoordinated jerking movements primarily affecting the face, hands and feet. [13] It is a result of an autoimmune response that occurs following infection by group A β-hemolytic streptococci (GABHS) [ 14 ] that destroys cells in the corpus striatum of the basal ganglia .
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