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163 million (2017) [ 8 ] Major depressive disorder (MDD), also known as clinical depression, is a mental disorder [ 9 ] characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, [ 10 ] the term was ...
A major depressive episode (MDE) is a period characterized by symptoms of major depressive disorder. Those affected primarily exhibit a depressive mood for at least two weeks or more, and a loss of interest or pleasure in everyday activities. Other symptoms can include feelings of emptiness, hopelessness, anxiety, worthlessness, guilt ...
Emotions. v. t. e. Depression is a mental state of low mood and aversion to activity. [3] It affects about 3.5% of the global population, or about 280 million people of all ages (as of 2020). [4] Depression affects a person's thoughts, behavior, feelings, and sense of well-being. [5]
Sleep disturbances: Sleep disruptions, such as insomnia, oversleeping, or waking up too early are symptoms of depression that are more likely to be reported in men than women. Fatigue: Persistent ...
Late-life depression is often underdiagnosed, which is due to numerous reasons, including that depressed mood is commonly not as prominent as other somatic and psychotic symptoms such as loss of appetite, disruptions in sleep, lack of energy or anergia, fatigue, and loss of interest and enjoyment in normal life activities. [3][4] Concurrent ...
Mood swings in Premenstrual symptoms (PMS): Episodically at mild to severe degree in the menses period, occur gradually or rapidly, [ 49 ] start 7 days before and decrease at the onset of menses. [ 50 ] Characterized by angry outbursts, depression, anxiety, confusion, irritability or social withdrawal.
Bipolar disorder, previously known as manic depression, is a mental disorder characterized by periods of depression and periods of abnormally elevated mood that each last from days to weeks. [4][5] If the elevated mood is severe or associated with psychosis, it is called mania; if it is less severe and does not significantly affect functioning ...
Biology of depression. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD), [ 1 ] and this has encouraged advocates of various theories that seek to identify a biochemical origin of the disease, as opposed to theories that emphasize psychological or situational causes.