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This gene is highly expressed in the brain and may function as an integrin ligand in the brain. [19] ADAM23: This gene is highly expressed in the brain and may function as an integrin ligand in the brain. [20] ADAM28: The protein encoded by this gene is a lymphocyte-expressed ADAM protein. [21] ADAM29: ADAM30: ADAM33
The human brain is the central organ of the human nervous system, and with the spinal cord, comprises the central nervous system. It consists of the cerebrum, the brainstem and the cerebellum. The brain controls most of the activities of the body, processing, integrating, and coordinating the information it receives from the sensory nervous ...
The form of neural plasticity known as long-term potentiation (LTP) was initially discovered to occur in the hippocampus and has often been studied in this structure. LTP is widely believed to be one of the main neural mechanisms by which memories are stored in the brain.
The brain is small and simple in some species, such as nematode worms; in other species, such as vertebrates, it is a large and very complex organ. [4] Some types of worms, such as leeches, also have an enlarged ganglion at the back end of the nerve cord, known as a "tail brain". [17]
CA4 is a misleading term introduced by Lorente de Nó. [10] He observed that the pyramidal layer of the CA3 was continuous with polymorphic layer of the dentate gyrus and that the "modified pyramids" (later known as mossy cells [11]) had Schaffer collaterals similar to CA3 pyramidal cells.
The choroid plexus regulates the production and composition of cerebrospinal fluid (CSF), that provides the protective buoyancy for the brain. [2] [10] CSF acts as a medium for the glymphatic filtration system that facilitates the removal of metabolic waste from the brain, and the exchange of biomolecules and xenobiotics into and out of the brain.
The arachnoid mater covering the brain is referred to as the arachnoidea encephali, and the portion covering the spinal cord as the arachnoidea spinalis. The arachnoid and pia mater are sometimes considered as a single structure, the leptomeninx, or the plural version, leptomeninges ( lepto , from the Greek root meaning "thin" or "slender").
Blood–brain barrier: The astrocyte endfeet processes encircling endothelial cells were thought to aid in the maintenance of the blood–brain barrier, and recent research indicates that they do play a substantial role, along with the tight junctions and basal lamina.