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ISRIB (short for "integrated stress response inhibitor") is an experimental drug that reverses the effects of eIF2α phosphorylation with an IC 50 of 5 nM.It was discovered in the laboratory of Peter Walter at University of California, San Francisco (UCSF) through a semi-automated screening of a large library of small molecules by Carmela Sidrauski, who decided to pursue research on it.
Induced systemic resistance (ISR) is a resistance mechanism in plants that is activated by infection. Its mode of action does not depend on direct killing or inhibition of the invading pathogen , but rather on increasing physical or chemical barrier of the host plant. [ 1 ]
ISR is the coordinated and integrated acquisition, processing and provision of timely, accurate, relevant, coherent and assured information and intelligence to support commander's conduct of activities. Land, sea, air and space platforms have critical ISR roles in supporting operations in general.
The main reason behind the internal strife was indecision over the future of the aircraft carrier fleet and their air wings, between better UAV-based ISR coverage integrated on board carriers in the near-future and integrating a new unmanned aircraft into the carrier air wing to make the carrier a more effective strike platform. [23]
On 14 July 2014, the Secretary and Chief of Staff of the Air Force announced that the Air Force ISR Agency would be reorganized into the Twenty-Fifth Air Force (25 AF), a numbered air force assigned to Air Combat Command, on 1 October 2014.
Sudanese women tell Human Rights Watch that RSF paramilitaries, one side in a grueling civil war, are subjecting them to horrific sexual violence.
Systemic acquired resistance (SAR) is a "whole-plant" resistance response that occurs following an earlier localized exposure to a pathogen.SAR is analogous to the innate immune system found in animals, and although there are many shared aspects between the two systems, it is thought to be a result of convergent evolution. [1]
Abu Mohammad al-Jolani’s road to Damascus has been long. He has talked openly about his change along the way. From young al Qaeda fighter two decades ago, to rebel commander espousing sectarian ...