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Normal volume hypernatremia can be due to fever, extreme thirst, prolonged increased breath rate, diabetes insipidus, and from lithium among other causes. [1] High volume hypernatremia can be due to hyperaldosteronism, excessive administration of intravenous normal saline or sodium bicarbonate, or rarely from eating too much salt.
There are three types of hypernatremia each with different causes. [3] The first is dehydration along with low total body sodium. This is most commonly caused by heatstroke, burns, extreme sweating, vomiting, and diarrhea. [3] The second is low total body water with normal body sodium.
In summary, hyperaldosteronism causes hypernatremia, hypokalemia, and metabolic alkalosis. [ 13 ] Finer notes on aldosterone include the fact that it stimulates sodium-potassium ATPase in muscle cells , increasing intracellular potassium and also increases sodium reabsorption all along the intestine and nephron , possibly due to widespread ...
Hypernatremia (high blood sodium level, above 145 mEq/L) causes thirst, and due to brain cell shrinkage may cause confusion, muscle twitching, or spasms. With severe elevation, seizures and comas may occur. [11] [12] Death can be caused by ingestion of large amounts of salt at a time (about 1 g per kg of body weight). [13]
12 Hypernatremia (signs and symptoms) 13 Inflammatory Bowel Disease: ... 3 common causes, 3 rarer causes. Common are 3 C's: Cirrhosis Carcinoma Cardiac failure
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