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Biomarkers are usually required to aid the selection of patients who will likely respond to a given targeted therapy. [6] Co-targeted therapy involves the use of one or more therapeutics aimed at multiple targets, for example PI3K and MEK, in an attempt to generate a synergistic response [5] and prevent the development of drug resistance. [7] [8]
Cancer treatments are a wide range of treatments available for the many different types of cancer, with each cancer type needing its own specific treatment. [1] Treatments can include surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy including small-molecule drugs or monoclonal antibodies, [2] and PARP inhibitors such as olaparib. [3]
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Targeted agents are beginning to permit the design of more rational treatment regimens for non-small cell lung cancer (NSCLC), which comprises about 80% to 85% of all lung cancers. [ 3 ] [ 4 ] [ 18 ] While there have been no randomized clinical trials of targeted agents in combined small-cell lung carcinoma (c-SCLC), [ citation needed ] some ...
Targeted alpha-particle therapy (or TAT) is an in-development method of targeted radionuclide therapy of various cancers. It employs radioactive substances which undergo alpha decay to treat diseased tissue at close proximity. [1] It has the potential to provide highly targeted treatment, especially to microscopic tumour cells.
The Chief of the General Staff performs the task of advising the Minister of Defense in terms of state management and military command, by that practically being the second highest-ranking professional leader of the Vietnam People’s Army alongside the Chief of the General Department of Political Affairs.
He held the post until June 7th 2022, when he was relieved of duty by the National Assembly following corruption allegations regarding the Viet A COVID-19 test kit scandal. [ 14 ] On July 15, 2022, Ms. Dao Hong Lan took office as Minister of Health, [ 15 ] [ 16 ] [ 17 ] replacing Mr. Nguyen Thanh Long , after the discovery of scandals related ...
First-line therapy (sometimes referred to as induction therapy, primary therapy, or front-line therapy) [3] is the first therapy that will be tried. Its priority over other options is usually either: (1) formally recommended on the basis of clinical trial evidence for its best-available combination of efficacy, safety, and tolerability or (2 ...