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In June 2012, the U.S. Food and Drug Administration (FDA) approved a combination vaccine against two types of meningococcal diseases and Hib disease for infants and children 6 weeks to 18 months old. The vaccine, Menhibrix , was designed to prevent disease caused by Neisseria meningitidis serogroups C and Y, and Haemophilus influenzae type b (Hib).
Meningococcal meningitis is a form of bacterial meningitis. Meningitis is a disease caused by inflammation and irritation of the meninges , the membranes surrounding the brain and spinal cord. In meningococcal meningitis this is caused by the bacteria invading the cerebrospinal fluid and circulating through the central nervous system .
In cases of meningococcal meningitis, preventative treatment in close contacts with antibiotics (e.g. rifampicin, ciprofloxacin or ceftriaxone) can reduce their risk of contracting the condition, but does not protect against future infections. [48] [69] Resistance to rifampicin has been noted to increase after use, which has caused some to ...
N. meningitidis (also called the meningococcus) is one of the most common causes of bacterial meningitis and the causative agent of meningococcal septicaemia. The immune system's neutrophils are restricted in function due to the ability of Neisseria to evade opsonization by antibodies, and to replicate within neutrophils despite phagocytosis.
The first-of-its-kind shot addresses the five most common causes of meningococcal disease, Pfizer says. Skip to main content. 24/7 Help. For premium support please call: 800-290-4726 more ways ...
Methicillin-resistant S. aureus has generated growing concerns over its resistance to almost all antibiotics except vancomycin. However, most serious S. aureus infections in the community, and many in hospitals, are caused by methicillin-susceptible isolates (MSSA) and there have been few attempts to identify the hypervirulent MSSA clones ...
NmVac4-A/C/Y/W-135 is the commercial name for a polysaccharide vaccine that protects against meningococcal meningitis caused by Neisseria meningitidis, specifically the serotypes A, C, Y, and W-135. This vaccine is part of a broader group of meningococcal vaccines .
Neisseria meningitidis causes meningococcal meningitis and sepsis. Opc (formerly called 5C) is one of the major outer membrane proteins and has been shown to play an important role in meningococcal adhesion and invasion of epithelial and endothelial cells, mediating attachment to host cells by binding proteoglycan cell-surface receptors. [1]
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