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  2. Sex-determining region Y protein - Wikipedia

    en.wikipedia.org/wiki/Sex-determining_region_y...

    In humans, the SRY gene is located on short (p) arm of the Y chromosome at position 11.2. Sex-determining region Y protein (SRY), or testis-determining factor (TDF), is a DNA-binding protein (also known as gene-regulatory protein/transcription factor) encoded by the SRY gene that is responsible for the initiation of male sex determination in therian mammals (placentals and marsupials). [5]

  3. Sex cords - Wikipedia

    en.wikipedia.org/wiki/Sex_cords

    If there is a Y chromosome present, testicular cords will develop via the Sry gene (on the Y chromosome): repressing the female sex cord genes and activating the male. [ 4 ] [ 5 ] If there is no Y chromosome present the opposite will occur, developing ovarian cords.

  4. Sexual differentiation in humans - Wikipedia

    en.wikipedia.org/wiki/Sexual_differentiation_in...

    The human Y chromosome showing the SRY gene which codes for a protein regulating sexual differentiation. Sexual differentiation in humans is the process of development of sex differences in humans. It is defined as the development of phenotypic structures consequent to the action of hormones produced following gonadal determination. [1]

  5. XY gonadal dysgenesis - Wikipedia

    en.wikipedia.org/wiki/XY_gonadal_dysgenesis

    XY complete gonadal dysgenesis, also known as Swyer syndrome, is a type of defect hypogonadism in a person whose karyotype is 46,XY. Though they typically have normal vulvas, [1] the person has underdeveloped gonads, fibrous tissue termed "streak gonads", and if left untreated, will not experience puberty.

  6. XX male syndrome - Wikipedia

    en.wikipedia.org/wiki/XX_male_syndrome

    The tip of the Y chromosome contains the SRY gene and, during recombination, a translocation occurs in which the SRY gene becomes part of the X chromosome. [15] [26] If a fetus is conceived from a sperm cell with an X chromosome bearing the SRY gene, it will develop as a male despite not having a Y chromosome. This form of the condition is ...

  7. Y linkage - Wikipedia

    en.wikipedia.org/wiki/Y_linkage

    Y-linked inheritance Pedigree tree showing the inheritance of a Y-linked trait. Y linkage, also known as holandric inheritance (from Ancient Greek ὅλος hólos, "whole" + ἀνδρός andrós, "male"), [1] describes traits that are produced by genes located on the Y chromosome.

  8. Category:Genes on human chromosome Y - Wikipedia

    en.wikipedia.org/wiki/Category:Genes_on_human...

    Download QR code; Print/export Download as PDF; Printable version; In other projects ... Short-stature homeobox gene; SRY gene; T. Thymosin beta-4, Y-chromosomal ...

  9. Sex-determination system - Wikipedia

    en.wikipedia.org/wiki/Sex-determination_system

    Once the SRY gene is activated, cells create testosterone and anti-müllerian hormone which typically ensures the development of a single, male reproductive system. [9] In typical XX embryos, cells secrete estrogen, which drives the body toward the female pathway. In Y-centered sex determination, the SRY gene is the main gene in determining ...