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Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by patches of abnormal skin. [4][5] These areas are red, pink, or purple, dry, itchy, and scaly. [8][3] Psoriasis varies in severity from small localized patches to complete body coverage. [3] Injury to the skin can trigger psoriatic skin changes at that spot, which is ...
The Rule of Tens is a concept to aid clinicians in making the diagnosis of “severe psoriasis”. [39] It states that a patient is considered to have “severe psoriasis” if their body surface area affected is >10%, or if their Psoriasis Area and Severity Index (PASI) score is >10, or if the DLQI score is >10. [39]
Psoriatic arthritis (PsA) is a long-term inflammatory arthritis that occurs in people affected by the autoimmune disease psoriasis. [1][2] The classic feature of psoriatic arthritis is swelling of entire fingers and toes with a sausage-like appearance ("sausage digit"). [3]
In the European Union, in combination with methotrexate, tofacitinib citrate is indicated for the treatment of moderate to severe active rheumatoid arthritis (RA) in adults who have responded inadequately to, or who are intolerant to one or more disease-modifying antirheumatic drugs. [9] It can be given as monotherapy in case of intolerance to ...
Goeckerman therapy is a regimen for treatment of moderate to severe plaque psoriasis using a combination of crude coal tar and artificial ultraviolet radiation. It is a specialized form of light therapy. First formulated in 1925 by American dermatologist William H. Goeckerman (1884–1954), Goeckerman therapy continues to be used due to its ...
PUVA (psoralen and UVA) is an ultraviolet light therapy treatment for skin diseases: vitiligo, eczema, psoriasis, graft-versus-host disease, mycosis fungoides, large plaque parapsoriasis, and cutaneous T-cell lymphoma, using the sensitizing effects of the drug psoralen. [1]: 686 [2][3] The psoralen is applied or taken orally to sensitize the ...
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