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In Pa, 78 merges into 81. Merge onto I-81 S Passing through Maryland, West Virginia and into Virginia Take exit 81 to merge onto I-77 S toward Charlotte NC Passing through North Carolina, Entering South Carolina Keep left at the fork, follow signs for I-26 E/Charleston and merge onto I-26 E Take exit 169A to merge onto I-95 S toward Savannah
Probably the easiest way to get from I-81 to I-95 near Fredericksburg, VA is to get on I-66 near Strasburg, VA, take that 25-30 miles and then get on US-17 (also called Winchester Road). You get on US 17 from I-66 before the DC area traffic really gets to be a factor, and US 17 is a pretty decent road.
Going from Allentown, PA to Myrtle Beach, SC via I-81 and I-74 (which is a better choice than I-77 which goes further south to Charlotte) is anywhere from 1.5 - 2 hours longer than taking I-95 South. I personally would take I-95 South from Allentown and then go around DC as mentioned above
According to google maps, the difference between going PHL to Charlotte via 95 and going 81 via Harrisburg is about 29 miles (give or take). I'm sure the ride from Harrisburg down 81 is a much nicer ride. However, the last time I used 81 south of Hburg, there was some construction.
Actually, it's I-66 that leads from I-81 near Front Royal east to DC and the beltway. I-64 goes east from I-81 near Staunton toward Richmond and Norfolk, well south of the DC area. It's been a while since I've been on I-66, but IIRC it's a zoo from Manassas on in to the beltway.
On holiday weekends, I-81 can save some time as there are few non-peak periods, but I'd recommend taking I-64 off I-81 and then VA 288 around Richmond to pickup I-95 just south of Richmond. This gets you around the worst potential areas of I-95 and gets you back on I-95 earlier for the best parts of the I-95 route.
Sep 22, 2010. #12. I-66 is fine between I-81 and Route 17, very minimal (if any) road construction. Traffic will be heavy during rush hour but should move steadily at posted speeds. Route 17 from I-66 to I-95 is all 4 lane with some stop lights but they don't slow traffic appreciably.
Messages. 3,566. Nov 23, 2006. #6. misslissa said: There are only three routes. I75, very flat, urban all of the way... safest in winter. I77/79, through the mountains, very "country" (2 lane highways), the quickest way... don't take if you have an RV or SUV. I95, very few people take this route, it is further and travels mostly down the east ...
7,427. Jul 26, 2016. #3. We drive from MA to Hilton Head, SC a couple times a year. 95 is obviously the shortest route but far from least stressful. On our way home this past April we got stuck in traffic before Richmond and decided to take "the road less traveled" and just work our way north.
The I-95 route is much shorter for us than the I-81 side trip. We took an side trip once that was shorter (mileage) than the I-81/I-77 route, and it added about 2-1/2 hours to our travel time. This was on state routes, not interstates, where the speed limit was usually 45-55 mph with no traffic.