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What is the most common cause of an enlarged liver? Common causes include: Alcohol-associated hepatitis, either chronic or acute. Toxic hepatitis, often due to a medication overdose. Viral hepatitis due to infection with hepatitis A, B or C. Fatty liver disease, due to alcohol or metabolic syndrome. Mononucleosis, a common viral infection.
The medical term is hepatomegaly (hep-uh-toe-MEG-uh-le). Rather than a disease, an enlarged liver is a sign of an underlying problem, such as liver disease, congestive heart failure or cancer. Treatment involves identifying and controlling the cause of the condition.
Hepatomegaly Causes. Your liver might be enlarged because of one of these things: Inflammation or fatty liver. This could be from: Obesity; An infection (such as hepatitis B or hepatitis C)
NAFLD ranges in severity from hepatic steatosis, called fatty liver, to a more severe form of disease called nonalcoholic steatohepatitis (NASH). NASH causes the liver to swell and become damaged due to the fat deposits in the liver. NASH may get worse and may lead to serious liver scarring, called cirrhosis, and even liver cancer.
Some conditions that can cause hepatomegaly include fatty liver disease, alcohol use disorder, hepatitis, and cancer. A person may have hepatomegaly and not be aware of it.
Steatosis occurs when liver cells accumulate fat in response to injury. Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly known as nonalcoholic fatty liver disease or NAFLD) refers to an accumulation of fat in the liver not caused by alcohol, viral infection, medications, or genetic disease.
Hepatomegaly is when you have an enlarged liver. It’s often a sign of a serious health concern. Your liver is the largest internal organ. It helps your body: digest fats. store sugar in the form...