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A megakaryoblast (from mega- 'large' karyo- 'cell nucleus' and -blast 'precursor cell') is a precursor cell to a promegakaryocyte. During thrombopoiesis , the promegakaryocyte matures into the form of a megakaryocyte .
It has been discovered that these cells have a high replating efficiency, meaning that when taken from the umbilical cord and grown in culture, a high percentage of these cells are able to produce colonies. The results of studies conducted by Carow, Hangoc, and Broxmeyer in 1993 reveal that the CFU-GEMM can be classified as a stem cell due to ...
A megakaryocyte (from mega- 'large' karyo- 'cell nucleus' and -cyte 'cell') is a large bone marrow cell with a lobated nucleus that produces blood platelets (thrombocytes), which are necessary for normal clotting.
A precursor cell is a stem cell with the capacity to differentiate into only one cell type, meaning they are unipotent stem cells. In embryology, precursor cells are a group of cells that later differentiate into one organ. However, progenitor cells are considered multipotent. [1]
Further proof that these Touton giant cells are histiocytic in origin, meaning they arise from a macrophage-lineage cell, is the fact they react positively to enzymes found in histiocytes such as lysozyme, alpha 1-anti-trypsin and alpha 1-anti-chymotrypsin. Touton giant cells are able to express these proteins which are involved in actions such ...
In hematology, myelopoiesis in the broadest sense of the term is the production of bone marrow and of all cells that arise from it, namely, all blood cells. [1] In a narrower sense, myelopoiesis also refers specifically to the regulated formation of myeloid leukocytes (), including eosinophilic granulocytes, basophilic granulocytes, neutrophilic granulocytes, and monocytes.
Histopathologic image of aspiration pneumonia in an elderly patient with debilitating neurologic illness. Note foreign-body giant cell reaction. Autopsy case. H & E stain. A foreign-body giant cell is a collection of fused macrophages which are generated in response to the presence of a large foreign body.
A proerythroblast (or rubriblast, or pronormoblast) is a precursor cell to the normoblast (nucleated red blood cell), as the earliest of four stages in its development.. In histology, it is very difficult to distinguish it from the other "-blast" cells (lymphoblast, myeloblast, monoblast, and megakaryoblast).