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  2. Demeclocycline - Wikipedia

    en.wikipedia.org/wiki/Demeclocycline

    The side effects are similar to those of other tetracyclines. Skin reactions with sunlight have been reported. [15] Like only few other known tetracycline derivatives, demeclocycline causes nephrogenic diabetes insipidus. [16] Furthermore, demeclocycline might have psychotropic side effects similar to lithium. [17]

  3. Syndrome of inappropriate antidiuretic hormone secretion

    en.wikipedia.org/wiki/Syndrome_of_inappropriate...

    Demeclocycline can be used in chronic situations when fluid restrictions are difficult to maintain; demeclocycline is the most potent inhibitor of Vasopressin (ADH/AVP) action. However, demeclocycline has a 2–3 day delay in onset with extensive side effect profile, including skin photosensitivity, and nephrotoxicity. [19]

  4. Primary polydipsia - Wikipedia

    en.wikipedia.org/wiki/Primary_polydipsia

    Demeclocycline, a tetracycline antibiotic, which is effective due to the side effect of inducing nephrogenic diabetes insipidus. [ 30 ] [ 36 ] Demeclocycline is used for cases of psychogenic polydipsia, including those with nocturnal enuresis (bed-wetting).

  5. Loop diuretic - Wikipedia

    en.wikipedia.org/wiki/Loop_diuretic

    Hypertension - A systematic review by the Cochrane Hypertension group assessing the anti-hypertensive effects of loop diuretics found only a modest reduction in blood pressure when compared to placebo. [14] According to Joint National Committee (JNC-8) guidelines, the first line treatment of hypertension is thiazide diuretics. The use of loop ...

  6. Vasopressin receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/Vasopressin_receptor...

    The "vaptan" drugs act by directly blocking the action of vasopressin at its receptors (V 1A, V 1B and V 2).These receptors have a variety of functions, with the V 1A and V 2 receptors are expressed peripherally and involved in the modulation of blood pressure and kidney function respectively, while the V 1A and V 1B receptors are expressed in the central nervous system.

  7. Acetazolamide - Wikipedia

    en.wikipedia.org/wiki/Acetazolamide

    Acetazolamide is a first generation carbonic anhydrase inhibitor and it decreases the ocular fluid and osmolality in the eye to decrease intraocular pressure. [5] [6] Common side effects include numbness, ringing in the ears, loss of appetite, vomiting, and sleepiness. [2]

  8. Netarsudil - Wikipedia

    en.wikipedia.org/wiki/Netarsudil

    Netarsudil, sold under the brand name Rhopressa among others, is a medication for the treatment of glaucoma. [1] [2] [3] In the United States, in December 2017, the Food and Drug Administration (FDA) approved a 0.02% ophthalmic solution for the lowering of elevated intraocular pressure in people with open-angle glaucoma or ocular hypertension.

  9. Comparison of bicalutamide with other antiandrogens

    en.wikipedia.org/wiki/Comparison_of_bicalutamide...

    Unlike spironolactone, bicalutamide has no antimineralocorticoid activity, [97] and for this reason, has no risk of hyperkalemia (which can, rarely/in severe cases, result in hospitalization or death) [112] or other antimineralocorticoid side effects such as urinary frequency, dehydration, hypotension, hyponatremia, metabolic acidosis, or ...