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  2. Hemolytic–uremic syndrome - Wikipedia

    en.wikipedia.org/wiki/Hemolytic–uremic_syndrome

    Hemolytic–uremic syndrome (HUS) is a group of blood disorders characterized by low red blood cells, acute kidney injury (previously called acute renal failure), and low platelets. [1] [3] Initial symptoms typically include bloody diarrhea, fever, vomiting, and weakness. [1] [2] Kidney problems and low platelets then occur as the diarrhea ...

  3. Paroxysmal nocturnal hemoglobinuria - Wikipedia

    en.wikipedia.org/wiki/Paroxysmal_nocturnal...

    Danicopan, sold under the brand name Voydeya, is a medication used for the treatment of paroxysmal nocturnal hemoglobinuria. It is a complement inhibitor which reversibly binds to factor D to prevent alternative pathway-mediated hemolysis and deposition of complement C3 proteins on red blood cells. The most common side effects include fever, headache, increased levels of liver enzymes (a sign ...

  4. Atypical hemolytic uremic syndrome - Wikipedia

    en.wikipedia.org/wiki/Atypical_hemolytic_uremic...

    Atypical hemolytic uremic syndrome (aHUS), also known as complement-mediated hemolytic uremic syndrome (not to be confused with hemolytic–uremic syndrome), is an extremely rare, life-threatening, progressive disease that frequently has a genetic component. In most cases, it can be effectively controlled by interruption of the complement cascade.

  5. Nephritic syndrome - Wikipedia

    en.wikipedia.org/wiki/Nephritic_syndrome

    Hemolytic uremic syndrome - Most cases occur immediately following infectious diarrhea caused by a specific type of E. coli . The bacteria produces a toxin that causes widespread inflammation and numerous blood clots in small blood vessels ( thrombotic microangiopathy ).

  6. Hemoglobinuria - Wikipedia

    en.wikipedia.org/wiki/Hemoglobinuria

    Hemoglobinuria is a condition in which the oxygen transport protein hemoglobin is found in abnormally high concentrations in the urine. [1] The condition is caused by excessive intravascular hemolysis, in which large numbers of red blood cells (RBCs) are destroyed, thereby releasing free hemoglobin into the plasma. [2]

  7. Uremia - Wikipedia

    en.wikipedia.org/wiki/Uremia

    Uremia is the condition of having high levels of urea in the blood. Urea is one of the primary components of urine.It can be defined as an excess in the blood of amino acid and protein metabolism end products, such as urea and creatinine, which would normally be excreted in the urine.

  8. Eculizumab - Wikipedia

    en.wikipedia.org/wiki/Eculizumab

    Eculizumab, sold under the brand name Soliris among others, is a recombinant humanized monoclonal antibody used to treat paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, generalized myasthenia gravis, and neuromyelitis optica.

  9. Hus - Wikipedia

    en.wikipedia.org/wiki/Hus

    Hemolytic–uremic syndrome, a group of blood disorders characterized by low red blood cells, acute kidney injury, and low platelets House ( Hus ), a single-unit residential building Huastec language (ISO 639-3 code: hus), spoken by the Téenek people living in rural areas of San Luis Potosí and northern Veracruz