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Zinc pyrithione (or pyrithione zinc) is a coordination complex of zinc. It has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis [ 2 ] and dandruff .
If you experience eczema or dandruff, excessive scratching on the scalp can even lead to scabbing. ... (anti-dandruff shampoo containing Zinc Pyrithione or Selenium Sulfide), ... coal tar, zinc ...
Try looking for ingredients like zinc pyrithione, selenium sulfide, ketoconazole, or salicylic acid. Hair type can influence treatment options for seborrheic dermatitis, says Dr. Woolery-Lloyd.
Seborrhoeic dermatitis of the scalp is often treated with shampoo preparations of ketoconazole zinc pyrithione, and selenium, although the latter has been partly discontinued due to concerns of selenium in higher concentrations being carcinogenic. [11]
Like selenium sulfide, zinc pyrithione (a zinc complex with two chelating pyrithione anions) also reduces epidermal turnover and inhibits fungal growth. [3] [unreliable medical source?] It is often administered with ketoconazole for better results. The symptoms do not resolve completely even after prolonged medication.
Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff, seborrhoeic dermatitis and eczema. [2] Climbazole has shown a high in vitro and in vivo efficacy against Malassezia spp. that appear to play an important role in the pathogenesis of dandruff. [2]
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