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Hematuria that occurs throughout urination suggests that bleeding is occurring above the level of the bladder. [5] Many causes may present as either visible hematuria or microscopic hematuria, and so the differential diagnosis is frequently organized based on glomerular and non-glomerular causes. [4] [6]
The glomerular basement membrane is a tissue in the kidney that filters the blood. An abnormal glomerular basement membrane may allow red blood cells into the urinary space. Because kidney stones are so common in people with LPHS, crystals in the kidney tubules may also play a part in bleeding and pain. [4] Other speculations on cause include [5]
External bleeding is generally described in terms of the origin of the blood flow by vessel type. The basic categories of external bleeding are: Arterial bleeding: As the name suggests, blood flow originating in an artery. With this type of bleeding, the blood is typically bright red to yellowish in colour, due to the high degree of oxygenation.
Thin basement membrane disease must be differentiated from the other two common causes of glomerular hematuria, IgA nephropathy and Alport syndrome. The history and presentation are helpful in this regard: [citation needed] In Alport syndrome, there is often a family history of kidney failure, which may be associated with hearing impairment.
That was in a 16-year-old girl who died 2 weeks after the abrupt onset and progression of petechial bleeding, pallor, fever, paralysis, hematuria and coma; and called "Moschcowitz disease". [ 52 ] [ 53 ] Moreover, Moschcowitz was among the first to work in psychosomatic medicine, and he presented a paper in 1935 on the psychological origins of ...
Goodpasture syndrome - This is a rare autoimmune disease where autoantibodies are produced that target the glomerular basement membrane in both the lungs and the kidneys. The damage to the basement membrane causes bleeding, and the disease often presents in patients as hematuria and haemoptysis (coughing up blood).
Injury: Two-fold increase in the serum creatinine, or GFR decrease by 50 percent, or urine output <0.5 mL/kg per hour for 12 hours. Failure: Three-fold increase in the serum creatinine, or GFR decrease by 75 percent, or urine output of <0.3 mL/kg per hour for 24 hours, or no urine output (anuria) for 12 hours.
Microhematuria, also called microscopic hematuria (both usually abbreviated as MH), is a medical condition in which urine contains small amounts of blood; the blood quantity is too low to change the color of the urine (otherwise, it is known as gross hematuria).