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Skin cancer is the most commonly diagnosed form of cancer in humans. [11] [12] [13] There are three main types of skin cancers: basal-cell skin cancer (BCC), squamous-cell skin cancer (SCC) and melanoma. [1] The first two, along with a number of less common skin cancers, are known as nonmelanoma skin cancer (NMSC).
Actinic keratosis (AK), sometimes called solar keratosis or senile keratosis, [1] [2] is a pre-cancerous [3] area of thick, scaly, or crusty skin. [4] [5] Actinic keratosis is a disorder of epidermal keratinocytes that is induced by ultraviolet (UV) light exposure ().
Clinical history and examination are important. In a significant number of patients there is a familial trait. Examination will white, translucent, slightly raised papules which have a pearly white appearance. Treatment: Any suspicicion of malignant change calls for adequate excision and histological examination.
This skin cancer tends to grow slowly and isn’t life-threatening for most people, but it needs to be treated before it can grow deep and injure nerves and blood vessels, the AAD noted.
In Canada, the most common skin cancer is basal-cell carcinoma (as much as one third of all cancer diagnoses), affecting 1 in 7 individuals over a lifetime. [66] This tumor accounts for approximately 70% of non-melanoma skin cancers. In 80 percent of all cases, basal-cell carcinoma affects head or neck skin. [65]
Keratoacanthoma is commonly found on sun-exposed skin, often face, forearms and hands. [2] [3] It is rarely found at a mucocutaneous junction or on mucous membranes. [2] Keratoacanthoma may be difficult to distinguish visually from a skin cancer. [4] Under the microscope, keratoacanthoma very closely resembles squamous cell carcinoma. In order ...
Cutaneous squamous-cell carcinoma is the second-most common cancer of the skin (after basal-cell carcinoma, but more common than melanoma). It usually occurs in areas exposed to the sun. Sunlight exposure and immunosuppression are risk factors for SCC of the skin, with chronic sun exposure being the strongest environmental risk factor. [26]
The stratum lucidum (Latin, 'clear layer') is a thin, clear layer of dead skin cells in the epidermis named for its translucent appearance under a microscope. It is readily visible by light microscopy only in areas of thick skin, which are found on the palms of the hands and the soles of the feet. [1] [2]