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  2. 2-Bromopentane - Wikipedia

    en.wikipedia.org/wiki/2-Bromopentane

    2-Bromopentane is a bromoalkane and isomer of bromopentane. It is a colorless liquid. 2-Bromopentane is chiral and thus can be obtained as either of two stereoisomers designated as ( R )-2-bromopentane and ( S )-2-bromopentane, or as a racemic 1:1 mixture of the two enantiomers .

  3. β-Hydroxybutyryl-CoA - Wikipedia

    en.wikipedia.org/wiki/Β-Hydroxybutyryl-CoA

    β-Hydroxybutyryl-CoA (or 3-hydroxybutyryl-coenzyme A) is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan. [1] [2] The L-3-hydroxybutyl-CoA (or (S)-3-hydroxybutanoyl-CoA) enantiomer is also the second to last intermediate in beta oxidation of even-numbered, straight chain, and saturated fatty acids.

  4. Absolute configuration - Wikipedia

    en.wikipedia.org/wiki/Absolute_configuration

    If a reaction gave the enantiomer of a known configuration, as indicated by the opposite sign of optical rotation, it would indicate that the absolute configuration is inverted. In 1951, Johannes Martin Bijvoet for the first time used in X-ray crystallography the effect of anomalous dispersion , which is now referred to as resonant scattering ...

  5. Bromopentane - Wikipedia

    en.wikipedia.org/wiki/Bromopentane

    Monobromopentanes are bromopentanes containing one bromine atom, with the formula C 5 H 11 Br.. There are three isomers of unbranched monobromopentane: 1-Bromopentane

  6. Enantiomer - Wikipedia

    en.wikipedia.org/wiki/Enantiomer

    An example of such an enantiomer is the sedative thalidomide, which was sold in a number of countries around the world from 1957 until 1961. It was withdrawn from the market when it was found to cause birth defects. One enantiomer caused the desirable sedative effects, while the other, unavoidably [23] present in equal quantities, caused birth ...

  7. Chiral drugs - Wikipedia

    en.wikipedia.org/wiki/Chiral_drugs

    The drug was withdrawn from world market when it became evident that the use in pregnancy causes phocomelia (clinical conditions where babies are born with deformed hand and limbs). Later in late 1970s studies indicated that the (R)- enantiomer is an effective sedative, the (S)-enantiomer harbors teratogenic effect and causes fetal abnormalities.

  8. Diastereomer - Wikipedia

    en.wikipedia.org/wiki/Diastereomer

    L-Threonine (2S,3R) and D-Threonine (2R,3S) L -Allothreonine (2 S ,3 S ) and D - Allothreonine (2 R ,3 R ) In alkene addition reactions, syn addition to a trans alkene, or anti addition to a cis alkene, gives a threo product, whereas syn addition to a cis alkene, or anti addition to a trans alkene, gives an erythro product.

  9. Dynamic kinetic resolution in asymmetric synthesis - Wikipedia

    en.wikipedia.org/wiki/Dynamic_Kinetic_Resolution...

    [2] [3] DKR utilizes a center of a particular molecule that can be easily epimerized so that the (R) and (S) enantiomers can interconvert throughout the reaction process. At this point the catalyst can selectively lower the transition state energy of a single enantiomer, leading to almost 100% yield of one reaction pathway over the other.