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Valaciclovir, also spelled valacyclovir, is an antiviral medication used to treat outbreaks of herpes simplex or herpes zoster (shingles). [2] It is also used to prevent cytomegalovirus following a kidney transplant in high risk cases. [ 2 ]
Similarly, Valtrex, first FDA approved in 2001 to treat persistent herpes outbreaks is a prodrug of acyclovir, first FDA approved in the mid-1980s. Valtrex metabolizes into acyclovir in the liver, [19] but when it first entered the market, it cost many times than the generic.
A U.S. patent on aciclovir listing Schaeffer as inventor was issued in 1979. [57] Vince later invented abacavir, an nRTI drug for HIV patients. [58] Elion was awarded the 1988 Nobel Prize in Medicine, partly for the development of aciclovir. [59] A related prodrug form, valaciclovir came into medical use in 1995. It is converted to aciclovir in ...
Valaciclovir (Valtrex) [20] Herpes Simplex/Zoster Valganciclovir (Valcyte) [21] Cytomegalovirus (CMV) Vicriviroc: HIV-1: Schering-Plough pyrimidine CCR5 entry inhibitor Vidarabine: Herpes Simplex, Varicella Zoster: Zalcitabine: HIV Zanamivir (Relenza) [22] Influenza A, Influenza B Zidovudine: HIV [23] Antiretroviral
Rank Brand Name(s) Generic Name Sales Q1 2014 Sales ($000) Change from Q4 2013 Company(ies) Disease/Medical Use First Approval Date Patent Expiration Date [6] [7]; 1: Abilify
E. W. Kemble's "Death's Laboratory" on the cover of Collier's (June 3, 1905). A patent medicine, also known as a proprietary medicine or a nostrum (from the Latin nostrum remedium, or "our remedy") is a commercial product advertised to consumers as an over-the-counter medicine, generally for a variety of ailments, without regard to its actual effectiveness or the potential for harmful side ...