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Both group A and group B coxsackieviruses can cause nonspecific febrile illnesses, rashes, upper respiratory tract disease, and aseptic meningitis. The basic reproduction number (R0) for Coxsackievirus A16 (Cox A16) was estimated to a median of 2.50 with an interquartile range of 1.96 to 3.67. [3]
Coxsackievirus infection on skin of adult. The most well known Coxsackie A disease is hand, foot and mouth disease (unrelated to foot-and-mouth disease), a common childhood illness which affects mostly children aged 5 or under, [7] often produced by Coxsackie A16.
Coxsackievirus A16 is the most common cause, and enterovirus 71 is the second-most common cause. [6] Other strains of coxsackievirus and enterovirus can also be responsible. [6] [12] Some people may carry and pass on the virus despite having no symptoms of disease. [10] Other animals are not involved. [8] Diagnosis can often be made based on ...
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HFMD, which is typically caused by coxsackieviruses in the U.S., is “quite contagious,” Dr. Jake Scott, infectious diseases physician at Stanford Medicine, tells Yahoo Life.
Thus, coxsackievirus A23 is the same serotype as echovirus 9, and coxsackievirus A15 is the same serotype as coxsackievirus A11 and coxsackievirus A18 is the same serotype as coxsackievirus A13. [citation needed] Life cycle of an enterovirus. Coxsackie A16 virus causes human hand, foot and mouth disease. [citation needed]
Herpangina, also called mouth blisters, is a painful mouth infection caused by coxsackieviruses.Usually, herpangina is produced by one particular strain of coxsackie virus A (and the term "herpangina virus" refers to coxsackievirus A), [1] but it can also be caused by coxsackievirus B or echoviruses. [2]
Coxsackievirus and adenovirus receptor (CAR) is a protein that in humans is encoded by the CXADR gene. [5] [6] [7] The protein encoded by this gene is a type I membrane receptor for group B coxsackie viruses and subgroup C adenoviruses. CAR protein is expressed in several tissues, including heart, brain, and, more generally, epithelial and ...