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The human body and even its individual body fluids may be conceptually divided into various fluid compartments, which, although not literally anatomic compartments, do represent a real division in terms of how portions of the body's water, solutes, and suspended elements are segregated. The two main fluid compartments are the intracellular and ...
The extracellular fluid, in particular the interstitial fluid, constitutes the body's internal environment that bathes all of the cells in the body. The ECF composition is therefore crucial for their normal functions, and is maintained by a number of homeostatic mechanisms involving negative feedback .
The extracellular fluid compartment is further subdivided into the interstitial fluid and the intravascular fluid compartments. Body fluids, bodily fluids, or biofluids, sometimes body liquids, are liquids within the body of an organism. [1] In lean healthy adult men, the total body water is about 60% (60–67%) of the total body weight; it is ...
In a 72 kg (159 lb) body containing 40 litres of fluid, about 25 litres is intracellular, [9] which amounts to 62.5%. Jackson's texts states 70% of body fluid is intracellular. [10] Extracellular fluid (1/3 of body water) is fluid contained in areas outside of cells. For a 40-litre body, about 15 litres is extracellular, [9] which amounts to 37.5%.
Euvolemia is the state of normal body fluid volume, including blood volume, interstitial fluid volume, and intracellular fluid volume; hypovolemia and hypervolemia are imbalances. Water is necessary for all life on Earth. Humans can survive for 4 to 6 weeks without food but only for a few days without water.
[1] [2] The fluid in this space is called interstitial fluid, comprises water and solutes, and drains into the lymph system. [2] The interstitial compartment is composed of connective and supporting tissues within the body – called the extracellular matrix – that are situated outside the blood and lymphatic vessels and the parenchyma of organs.
This space is usually taken to be outside the plasma membranes, and occupied by fluid (see extracellular matrix). The term is used in contrast to intracellular (inside the cell). According to the Gene Ontology , the extracellular space is a cellular component defined as: "That part of a multicellular organism outside the cells proper, usually ...
The pH of the intracellular fluid and the extracellular fluid need to be maintained at a constant level. [ 2 ] The three dimensional structures of many extracellular proteins, such as the plasma proteins and membrane proteins of the body's cells , are very sensitive to the extracellular pH.