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  2. Membrane potential - Wikipedia

    en.wikipedia.org/wiki/Membrane_potential

    When the membrane potential of a cell goes for a long period of time without changing significantly, it is referred to as a resting potential or resting voltage. This term is used for the membrane potential of non-excitable cells, but also for the membrane potential of excitable cells in the absence of excitation.

  3. Rheobase - Wikipedia

    en.wikipedia.org/wiki/Rheobase

    Thus, the strength-duration time constant is a reflection of persistent Na + channel function, and is furthermore influenced by membrane potential and passive membrane properties. [10] As such, many aspects of nerve excitability testing depend on sodium channel functions: namely, the strength-duration time constant, the recovery cycle, the ...

  4. Resting potential - Wikipedia

    en.wikipedia.org/wiki/Resting_potential

    Thus the membrane potential will not be right at E K, but rather depolarized from E K by an amount of approximately 5% of the 140 mV difference between E K and E Na. Thus, the cell's resting potential will be about −73 mV. In a more formal notation, the membrane potential is the weighted average of each contributing ion's equilibrium ...

  5. Threshold potential - Wikipedia

    en.wikipedia.org/wiki/Threshold_potential

    Most often, the threshold potential is a membrane potential value between –50 and –55 mV, [1] but can vary based upon several factors. A neuron's resting membrane potential (–70 mV) can be altered to either increase or decrease likelihood of reaching threshold via sodium and potassium ions.

  6. Biological neuron model - Wikipedia

    en.wikipedia.org/wiki/Biological_neuron_model

    Stochastic spike generation (noisy output) depends on the momentary difference between the membrane potential V(t) and the threshold. The membrane potential V of the spike response model (SRM) has two contributions. [51] [52] First, input current I is filtered by a first filter k. Second the sequence of output spikes S(t) is filtered by a ...

  7. Goldman equation - Wikipedia

    en.wikipedia.org/wiki/Goldman_equation

    The ionic charge determines the sign of the membrane potential contribution. During an action potential, although the membrane potential changes about 100mV, the concentrations of ions inside and outside the cell do not change significantly. They are always very close to their respective concentrations when the membrane is at their resting ...

  8. Graded potential - Wikipedia

    en.wikipedia.org/wiki/Graded_potential

    Graded potentials that make the membrane potential less negative or more positive, thus making the postsynaptic cell more likely to have an action potential, are called excitatory postsynaptic potentials (EPSPs). [4] Depolarizing local potentials sum together, and if the voltage reaches the threshold potential, an action potential occurs in ...

  9. Length constant - Wikipedia

    en.wikipedia.org/wiki/Length_constant

    Where voltage, V, is measured in millivolts, x is distance from the start of the potential (in millimeters), and λ is the length constant (in millimeters). V max is defined as the maximum voltage attained in the action potential, where: = where r m is the resistance across the membrane and I is the current flow.