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  2. Molecular pathology - Wikipedia

    en.wikipedia.org/wiki/Molecular_pathology

    Molecular pathology is commonly used in diagnosis of cancer and infectious diseases. Techniques are numerous but include quantitative polymerase chain reaction ( qPCR ), multiplex PCR , DNA microarray , in situ hybridization , in situ RNA sequencing, [ 3 ] DNA sequencing , antibody based immunofluorescence tissue assays, molecular profiling of ...

  3. Molecular diagnostics - Wikipedia

    en.wikipedia.org/wiki/Molecular_diagnostics

    PCR is currently the most widely used method for detection of DNA sequences. [22] The detection of the marker might use real time PCR, direct sequencing, [2]: ch 17 microarray chips—prefabricated chips that test many markers at once, [2]: ch 24 or MALDI-TOF [23] The same principle applies to the proteome and the genome.

  4. Cancer biomarker - Wikipedia

    en.wikipedia.org/wiki/Cancer_biomarker

    A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule." [18] In cancer research and medicine, biomarkers are used in three primary ways: [19] To help diagnose conditions, as in the case of identifying early stage cancers (diagnostic)

  5. Tumor marker - Wikipedia

    en.wikipedia.org/wiki/Tumor_marker

    A tumor marker is a biomarker that can be used to indicate the presence of cancer or the behavior of cancers (measure progression or response to therapy). They can be found in bodily fluids or tissue. Markers can help with assessing prognosis, surveilling patients after surgical removal of tumors, and even predicting drug-response and monitor ...

  6. Vectorette PCR - Wikipedia

    en.wikipedia.org/wiki/Vectorette_PCR

    The researchers were then able to produce numerous dominant markers with the use of Vectorette PCR that is based on a TE display that is nonradioactive. [16] Thyroid lymphoma is an illness which leads to the transformation of the lymphocytes belonging to the thyroid into cells of a cancerous nature. [17]

  7. MRNA-based disease diagnosis - Wikipedia

    en.wikipedia.org/wiki/MRNA-based_disease_diagnosis

    The mRNA-based disease diagnosis technologies have been applied to medical field widely in recent years, especially on early diagnosis of tumors (such as renal cell carcinoma, [2] hepatocellular carcinoma, [3] [4] breast cancer [5] and prostate cancer [6]). The technology can be applied to various types of samples depending on how easily the ...

  8. Biomarker - Wikipedia

    en.wikipedia.org/wiki/Biomarker

    In biomedical contexts, a biomarker, or biological marker, is a measurable indicator of some biological state or condition. Biomarkers are often measured and evaluated using blood, urine, or soft tissues [1] to examine normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. [2]

  9. EPIC-Seq - Wikipedia

    en.wikipedia.org/wiki/EPIC-Seq

    Using the single base or region level methylation percentages on detected cancer methylation markers for each cancer type, copy number ratios, and short/long fragment ratios; the method employs a custom Support Vector Machines algorithm to classify the cancer type if there exists one. This method reports the cancer detection and tissue-of ...

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