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Leo E. Hollister (December 3, 1920 - December 19, 2000) [1] was an American professor emeritus of medicine, psychiatry and pharmacology. [ 2 ] Work on hallucinogens
Different classes of hallucinogens have different pharmacological mechanisms of action. [2] [69] Psychedelics are 5-HT 2A receptor agonists (serotonin 2A receptor agonists). [70] [69] LSD, mescaline, psilocybin, and PCP are drugs that cause hallucinations, which can alter a person's perception of reality.
This is a list of investigational hallucinogens and entactogens, or hallucinogens and entactogens that are currently under formal development for clinical use but are not yet approved. [ 1 ] Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.
Salvia divinorum, a dissociative hallucinogenic sage. This is a list of plant species that, when consumed by humans, are known or suspected to produce psychoactive effects: changes in nervous system function that alter perception, mood, consciousness, cognition or behavior.
Mescaline, also known as mescalin or mezcalin, [8] and in chemical terms 3,4,5-trimethoxyphenethylamine, is a naturally occurring psychedelic protoalkaloid of the substituted phenethylamine class, known for its hallucinogenic effects comparable to those of LSD and psilocybin.
In 1943, Albert Hofmann discovered the hallucinogenic effects of LSD that led to an altered state of consciousness. [5] [6]In 1947, Gion Condrau and Arthur Stoll [5] [7] [8] [9] [6] observed that people diagnosed as "psychotics" had a stronger tolerance for LSD and that the effects of the drug were similar to the symptoms expressed by psychotics themselves.
Osmond's name appears in four footnotes in the book's early pages (in references to articles he wrote about medicinal use of hallucinogenic drugs). Osmond was respected and trusted enough that in 1955 he was approached by Christopher Mayhew, a politician, and guided Mayhew through a mescaline trip that was filmed for broadcast by the BBC. [8]
Richard A. Glennon is an American medicinal chemist who studies psychedelics, stimulants, entactogens, and other psychoactive drugs. [1] [2] [3] He has been an important pioneer of the use of animal drug discrimination tests in scientific research for studying psychoactive drugs like hallucinogens.