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Letrozole, sold under the brand name Femara among others, is an aromatase inhibitor medication that is used in the treatment of breast cancer for post-menopausal women. [ 1 ] It was patented in 1986 and approved for medical use in 1996. [ 4 ]
Ovarian stimulation with the aromatase inhibitor letrozole has been proposed for ovulation induction in order to treat unexplained female infertility. In a multi-center study funded by the National Institute of Child Health and Development, ovarian stimulation with letrozole resulted in a significantly lower frequency of multiple gestation (i.e., twins or triplets) but also a lower frequency ...
Warning: This article contains spoilers. 4 Pics 1 Word continues to delight and frustrate us. Occasionally, we'll rattle off four to five puzzles with little effort before getting stuck for ...
[4] [6] Peak levels of anastrozole occur a median 3 hours after administration, but with a wide range of 2 to 12 hours. [2] [4] Steady-state levels of anastrozole are achieved within 7 to 10 days of continuous administration, with 3.5-fold accumulation. [3] [2] [4] However, maximal suppression of estradiol levels occurs within 3 or 4 days of ...
Emotional dysregulation is characterized by an inability to flexibly respond to and manage emotional states, resulting in intense and prolonged emotional reactions that deviate from social norms, given the nature of the environmental stimuli encountered. Such reactions not only deviate from accepted social norms but also surpass what is ...
Alexithymia, also called emotional blindness, [1] is a neuropsychological phenomenon characterized by significant challenges in recognizing, expressing, feeling, sourcing, [2] and describing one's emotions. [3] [4] [5] It is associated with difficulties in attachment and interpersonal relations. [6]
"Alexithymia is a subclinical phenomenon involving a lack of emotional awareness or, more specifically, difficulty in identifying and describing feelings and in distinguishing feelings from the bodily sensations of emotional arousal" [13] At its core, alexithymia is an inability for an individual to recognize what emotions they are feeling—as ...
Appraisal: the emotional situation is evaluated and interpreted. Response: an emotional response is generated, giving rise to loosely coordinated changes in experiential, behavioral, and physiological response systems. Because an emotional response (4.) can cause changes to a situation (1.), this model involves a feedback loop from (4.)