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Glomerular filtration rate (GFR) is the volume of fluid filtered from the renal (kidney) glomerular capillaries into the Bowman's capsule per unit time. [4] Central to the physiologic maintenance of GFR is the differential basal tone of the afferent (input) and efferent (output) arterioles (see diagram).
The estimated glomerular filtration rate (eGFR) is a measure of kidney function. [6] Adding a race adjustment to kidney algorithms results in higher eGFR values in people identified as black. [7] [8] [9] Reasons for this vary, but it is thought to partially stem from the notion that Black persons are more muscular. [8]
EGFR signaling cascades Diagram of the EGF receptor highlighting important domains. Epidermal growth factor receptor (EGFR) is a transmembrane protein that is activated by binding of its specific ligands, including epidermal growth factor and transforming growth factor alpha (TGF-α). [7]
Race-based kidney function metrics, particularly normalizing creatinine, pose ethical challenges in diagnosing and managing chronic kidney disease (CKD). While certain racial and ethnic groups are at higher risk, using race as a reference range may reinforce stereotypes and perpetuate health disparities.
The TikTok video took viewers on a tour of “the smallest apartment that currently exists in New York City.” To call it an apartment is a stretch. To call it a studio is generous.
Heart failure with preserved ejection fraction (HFpEF) is a form of heart failure in which the ejection fraction – the percentage of the volume of blood ejected from the left ventricle with each heartbeat divided by the volume of blood when the left ventricle is maximally filled – is normal, defined as greater than 50%; [1] this may be measured by echocardiography or cardiac catheterization.
The 1954 24 Hours of Le Mans was a race for Sports Cars which took place on 12 and 13 June 1954, at the Circuit de la Sarthe, Le Mans, France. It was the 22nd 24 Hours of Le Mans and also the fourth race of the 1954 World Sportscar Championship. [1] The race was won by José Froilán González and Maurice Trintignant driving a Ferrari 375 Plus.
2:54 is a rock band formed in London in 2010, composed of Irish sisters Colette and Hannah Thurlow. Their songs focus on the shoegaze and alternative rock genres. Their songs focus on the shoegaze and alternative rock genres.