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  2. Proteolysis - Wikipedia

    en.wikipedia.org/wiki/Proteolysis

    The uncatalysed half-life is several hundred years. Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Protein degradation is a major regulatory mechanism of gene expression [1] and contributes substantially to shaping mammalian proteomes [2].

  3. Nirenberg and Matthaei experiment - Wikipedia

    en.wikipedia.org/wiki/Nirenberg_and_Matthaei...

    In the experiment, an extract was prepared from bacterial cells that could make protein without the presence of intact living cells. An artificial form of RNA consisting entirely of uracil-containing nucleotides (polyuridylic acid or poly-U) was added to the extract, causing it to form a protein composed entirely of the amino acid phenylalanine.

  4. Protein - Wikipedia

    en.wikipedia.org/wiki/Protein

    The understanding of proteins as polypeptides, or chains of amino acids, came through the work of Franz Hofmeister and Hermann Emil Fischer in 1902. [13] [14] The central role of proteins as enzymes in living organisms that catalyzed reactions was not fully appreciated until 1926, when James B. Sumner showed that the enzyme urease was in fact a ...

  5. Protein folding - Wikipedia

    en.wikipedia.org/wiki/Protein_folding

    Protein before and after folding Results of protein folding. Protein folding is the physical process by which a protein, after synthesis by a ribosome as a linear chain of amino acids, changes from an unstable random coil into a more ordered three-dimensional structure. This structure permits the protein to become biologically functional. [1]

  6. Cell theory - Wikipedia

    en.wikipedia.org/wiki/Cell_theory

    The generally accepted parts of modern cell theory include: All known living things are made up of one or more cells [13] All living cells arise from pre-existing cells by division. The cell is the fundamental unit of structure and function in all living organisms. [14] The activity of an organism depends on the total activity of independent ...

  7. Proteinoid - Wikipedia

    en.wikipedia.org/wiki/Proteinoid

    Fox has likened the amino acid globules to cells, and proposed it bridged the macromolecule to cell transition. However, his hypothesis was later dismissed as proteinoids are not proteins, they feature mostly non-peptide bonds and amino acid cross-linkages not present in living organisms. Furthermore, they have no compartmentalization and there ...

  8. Macromolecule - Wikipedia

    en.wikipedia.org/wiki/Macromolecule

    Each of these molecules is required for life since each plays a distinct, indispensable role in the cell. [11] The simple summary is that DNA makes RNA, and then RNA makes proteins . DNA, RNA, and proteins all consist of a repeating structure of related building blocks ( nucleotides in the case of DNA and RNA, amino acids in the case of proteins).

  9. Biomolecule - Wikipedia

    en.wikipedia.org/wiki/Biomolecule

    This protein was the first to have its structure solved by X-ray crystallography by Max Perutz and John Kendrew in 1958, for which they received a Nobel Prize in Chemistry. A biomolecule or biological molecule is loosely defined as a molecule produced by a living organism and essential to one or more typically biological processes. [1]