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  2. Tacrolimus - Wikipedia

    en.wikipedia.org/wiki/Tacrolimus

    Achieving target concentrations of tacrolimus is important – if levels are too low, then there is a risk of transplant rejection, if levels are too high, there is a risk of drug toxicities. There is evidence to suggest that dosing patients based on rs776746 genotype can result in faster and more frequent achievement of target tacrolimus levels.

  3. BK virus - Wikipedia

    en.wikipedia.org/wiki/BK_virus

    Although without any clinical symptoms, ... to be reduced to 100–150 ng/ml and tacrolimus levels reduced to 3–5 ng/ml ... found that low levels (< 40 μg/ml) and ...

  4. Hypoaldosteronism - Wikipedia

    en.wikipedia.org/wiki/Hypoaldosteronism

    Hypoaldosteronism causes low sodium (hyponatremia), high potassium (hyperkalemia), and metabolic acidosis, a condition in which the body produces excess acid.These conditions are responsible for the symptoms of hypoaldosteronism, which include muscle weakness, nausea, palpitations, irregular heartbeat, and abnormal blood pressure.

  5. Pseudohyperaldosteronism - Wikipedia

    en.wikipedia.org/wiki/Pseudohyperaldosteronism

    Pseudohyperaldosteronism (also pseudoaldosteronism) is a medical condition which mimics the effects of elevated aldosterone (hyperaldosteronism) by presenting with high blood pressure, low blood potassium levels (hypokalemia), metabolic alkalosis, and low levels of plasma renin activity (PRA).

  6. Immunosuppressive drug - Wikipedia

    en.wikipedia.org/wiki/Immunosuppressive_drug

    Tacrolimus (trade names Prograf, Astagraf XL, Envarsus XR) is a product of the bacterium Streptomyces tsukubensis. It is a macrolide lactone and acts by inhibiting calcineurin . The drug is used primarily in liver and kidney transplantations, although in some clinics it is used in heart, lung, and heart/lung transplantations.

  7. Six norovirus symptoms to watch out for as cases hit highest ...

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  8. Hypogammaglobulinemia - Wikipedia

    en.wikipedia.org/wiki/Hypogammaglobulinemia

    Screening of immunoglobulin levels in relatives of CVID and IgA patients finds a familial inheritance rate of 10% to 20%. In cases where a carrier of such a mutation would like to have children, preimplantation genetic diagnosis (PGD) has been offered. [2] PGD is defined as the testing of pre-implantation stage embryos or oocytes for genetic ...

  9. Immune reconstitution inflammatory syndrome - Wikipedia

    en.wikipedia.org/wiki/Immune_reconstitution...

    Immune reconstitution inflammatory syndrome (IRIS) is a condition seen in some cases of HIV/AIDS or immunosuppression, in which the immune system begins to recover, but then responds to a previously acquired opportunistic infection with an overwhelming inflammatory response that paradoxically makes the symptoms of infection worse.