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The most common complex found in blood consists of prolactin and immunoglobulin G (IgG). [1] While the free prolactin hormone is active, prolactin in the macroprolactin complex does not have any biological activity in the body and is considered benign. [2] However, macroprolactin is detected by all Laboratory tests that measure prolactin in ...
5617 19109 Ensembl ENSG00000172179 ENSMUSG00000021342 UniProt P01236 P06879 RefSeq (mRNA) NM_000948 NM_001163558 NM_001163530 NM_011164 RefSeq (protein) NP_000939 NP_001157030 NP_001157002 NP_035294 Location (UCSC) Chr 6: 22.29 – 22.3 Mb Chr 13: 27.24 – 27.25 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Prolactin (PRL), also known as lactotropin and mammotropin, is a protein ...
The magnitude that prolactin is elevated can be used as an indicator of the etiology of the hyperprolactinemia diagnosis. Prolactin levels over 250 ng/mL may suggest prolactinoma. Prolactin levels less than 100 ng/mL may suggest drug-induced hyperprolactinemia, macroprolactinemia, nonfunctioning pituitary adenomas, or systemic disorders.
Clinical or lab evidence of hyperandrogenism or high androgen levels. ... Cushing's syndrome and higher-than-normal prolactin hormone levels (aka hyperprolactinemia). A doctor may also do tests to ...
Hypoprolactinemia can result from autoimmune disease, [2] hypopituitarism, [1] growth hormone deficiency, [2] hypothyroidism, [2] excessive dopamine action in the tuberoinfundibular pathway and/or the anterior pituitary, and ingestion of drugs that activate the D 2 receptor, such as direct D 2 receptor agonists like bromocriptine and pergolide, and indirect D 2 receptor activators like ...
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...