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Hypertrophic osteoarthropathy is a medical condition combining clubbing and periostitis of the small hand joints, especially the distal interphalangeal joints and the metacarpophalangeal joints. Distal expansion of the long bones as well as painful, swollen joints [ 3 ] and synovial villous proliferation are often seen.
RS3PE typically involves the joints of the extremities, specifically the metacarpophalangeal and proximal interphalangeal joints, wrists, shoulders, elbows, knees and ankles. [4] It is more common in older adults, with the mean age between 70 and 80 years in most studies. [4] [5] It occurs more often in men than in women with a 2:1 ratio.
The most common symptoms are joint pain and stiffness. [1] Usually the symptoms progress slowly over years. [1] Other symptoms may include joint swelling, decreased range of motion, and, when the back is affected, weakness or numbness of the arms and legs. [1]
It typically results in warm, swollen, and painful joints. [1] Pain and stiffness often worsen following rest. [1] Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the body. [1] The disease may also affect other parts of the body, including skin, eyes, lungs, heart, nerves, and blood. [1]
Over time, this process contributes to joint pain, cartilage damage, bone erosion, swelling, and stiffness. [ 32 ] Gouty arthritis, commonly referred to as gout, is another form of inflammatory arthritis that can lead to hand deformities due to deposition of monosodium urate crystals in the joints and other tissues, forming nodular masses known ...
The most common initial presenting symptom of wrist osteoarthritis is joint pain. [7] [8] Other signs and symptoms, as with any joint affected by osteoarthritis, include: Loss of motion stiffness, which can be worse after a period of rest, such as when one awakes in the morning. Deformity of the wrist.
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