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  2. Metallopeptide - Wikipedia

    en.wikipedia.org/wiki/Metallopeptide

    De novo designed peptides which self-assemble in the presence of copper (Cu), forming supramolecular assemblies were presented by Korendovych et al. [8] Additionally there are examples of metallopeptides that are, at least partially, composed of non-natural amino acids with possible applications in drug discovery and biomaterials.

  3. Split and pool synthesis - Wikipedia

    en.wikipedia.org/wiki/Split_and_pool_synthesis

    The split and pool synthesis was first applied to prepare peptide libraries on solid support. The synthesis was realized in a home-made manual device shown in the figure. The device has a tube with 20 holes to which reaction vessels could be attached. One end of the tube is linked to a waste container and a water pump.

  4. Peptide synthesis - Wikipedia

    en.wikipedia.org/wiki/Peptide_synthesis

    In organic chemistry, peptide synthesis is the production of peptides, compounds where multiple amino acids are linked via amide bonds, also known as peptide bonds. Peptides are chemically synthesized by the condensation reaction of the carboxyl group of one amino acid to the amino group of another.

  5. Bimolecular fluorescence complementation - Wikipedia

    en.wikipedia.org/wiki/Bimolecular_fluorescence...

    For example, this may require the removal of proteins from their normal cellular environment. The processing required to isolate the protein may affect its interactions with other proteins. In addition, isolating the protein from the intracellular signaling and mechanisms that occur in the normal cell may provide a misleading picture of ...

  6. Peptidomimetic - Wikipedia

    en.wikipedia.org/wiki/Peptidomimetic

    Figure 1. Classification of peptidomimetics. [1]A peptidomimetic is a small protein-like chain designed to mimic a peptide. [1] [2] They typically arise either from modification of an existing peptide, or by designing similar systems that mimic peptides, such as peptoids and β-peptides.

  7. Bergmann azlactone peptide synthesis - Wikipedia

    en.wikipedia.org/wiki/Bergmann_azlactone_peptide...

    The Bergmann azlactone peptide synthesis is a classic organic synthesis process for the preparation of dipeptides. In the presence of a base, peptides are formed by aminolysis of N-carboxyanhydrides of amino acids with amino acid esters ( 1 ).

  8. Glycopeptide - Wikipedia

    en.wikipedia.org/wiki/Glycopeptide

    Glycopeptides are peptides that contain carbohydrate moieties covalently attached to the side chains of the amino acid residues that constitute the peptide.. Over the past few decades it has been recognised that glycans on cell surface (attached to membrane proteins or lipids) and those bound to proteins (glycoproteins) play a critical role in biology.

  9. Isobaric labeling - Wikipedia

    en.wikipedia.org/wiki/Isobaric_labeling

    Explained previously by (Lee, Choe, Aggarwal, 2017). [4] A key benefit of isobaric labeling over other quantification techniques (e.g. label-free) is the multiplex capabilities and thus increased throughput potential.

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