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A sterile version is used for making solutions that will be given by injection. [2] Before such use other substances generally must be added to make the solution isotonic. [3] Isotonic solutions containing water for injection can be given by injection into a vein, muscle, or under the skin. [4]
Ultrapure water (UPW), high-purity water or highly purified water (HPW) is water that has been purified to uncommonly stringent specifications. Ultrapure water is a term commonly used in manufacturing to emphasize the fact that the water is treated to the highest levels of purity for all contaminant types, including: organic and inorganic compounds; dissolved and particulate matter; volatile ...
Another class of ultrapure water used for pharmaceutical industries is called Water-For-Inject (WFI), typically generated by multiple distillation or compressed-vaporation [check spelling] process of DI water or RO-DI water. It has a tighter bacteria requirement as 10 CFU per 100 mL, instead of the 100 CFU per mL per USP.
USP establishes documentary (written) and reference (physical) standards for medicines, food ingredients, dietary supplement products, and ingredients. These standards are used by regulatory agencies and manufacturers to help to ensure that these products are of the appropriate identity, as well as strength, quality, purity, and consistency.
Acid-citrate-dextrose or acid-citrate-dextrose solution, also known as anticoagulant-citrate-dextrose or anticoagulant-citrate-dextrose solution (and often styled without the hyphens between the coordinate terms, thus acid citrate dextrose or ACD) is any solution of citric acid, sodium citrate, and dextrose in water.
Saline (also known as saline solution) is a mixture of sodium chloride (salt) and water. [1] It has a number of uses in medicine including cleaning wounds, removal and storage of contact lenses, and help with dry eyes. [2] By injection into a vein, it is used to treat hypovolemia such as that from gastroenteritis and diabetic ketoacidosis.
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Injector pens are an alternative to the manufacture of medication for injection in vials containing either liquid or a powder to which a diluent such as sterile water is added. When a vial is used as a means of storage, the end-user must use a syringe to "draw up" or remove the medication from the vial to prepare it for administration.