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Bicuspid aortic valves are the most common cardiac valvular anomaly, occurring in 1–2% of the general population. It is twice as common in males as in females. [23] Bicuspid aortic valve is a heritable condition, with a demonstrated association with mutations in the NOTCH1 gene. [24] Its heritability is as high as 89%. [25]
Normal aortic valve is tricuspid. Five types of bicuspid valve are shown, with Type 1 being most prevalent. Bicuspid valve forms when the tissue surrounding one of the cusps (leaflets) of the valve fuse during fetal development. This developmental anomaly can have either negative or no effect on the individual.
Mitral valve or bicuspid valve, between the left atrium and left ventricle; Two semilunar valves to prevent the backflow of blood into the ventricle: Pulmonary valve, located at the opening between the right ventricle and the pulmonary trunk; Aortic valve, located at the opening between the left ventricle and the aorta.
Cardiac physiology or heart function is the study of healthy, unimpaired function of the heart: involving blood flow; myocardium structure; the electrical conduction system of the heart; the cardiac cycle and cardiac output and how these interact and depend on one another.
The heart is a muscular organ situated in the mediastinum.It consists of four chambers, four valves, two main arteries (the coronary arteries), and the conduction system. The left and right sides of the heart have different functions: the right side receives de-oxygenated blood through the superior and inferior venae cavae and pumps blood to the lungs through the pulmonary artery, and the left ...
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Aortic valve repair or aortic valve reconstruction describes the reconstruction of both form and function of the native and dysfunctioning aortic valve. Most frequently it is applied for the treatment of aortic regurgitation. It can also become necessary for the treatment of aortic aneurysm, or less frequently for congenital aortic stenosis. [8]
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