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By pre-emptively treating patients who have become colonized with an antimicrobial resistant organism, the likelihood of the patient going on to develop life-threatening healthcare-associated infections is reduced. Common sites of bacterial colonization include the nasal passage, groin, oral cavity and skin. [1]
More recently, an interplay between bacterial colonization and increases in reactive oxygen species leading to formation and production of biofilms has been shown to generate chronic wounds. [23] Like ischemia, bacterial colonization and infection damage tissue by causing a greater number of neutrophils to enter the wound site. [2]
Virulence factors (preferably known as pathogenicity factors or effectors in botany) are cellular structures, molecules and regulatory systems that enable microbial pathogens (bacteria, viruses, fungi, and protozoa) to achieve the following: [1] [2] colonization of a niche in the host (this includes movement towards and attachment to host cells ...
Overuse of antimicrobial agents and problems with infection control practices have led to the development of multidrug-resistant gram-negative bacterial infections. We used to use carbapenems as the main option in several countries for those severe infections; however, now there are several mechanisms of resistance, including carbapenemase ...
Hosts can fight infections using their immune systems. Mammalian hosts react to infections with an innate response, often involving inflammation, followed by an adaptive response. Treatment for infections depends on the type of pathogen involved. Common medications include: Antibiotics for bacterial infections. Antivirals for viral infections.
Infectious diseases (ID), also known as infectiology, is a medical specialty dealing with the diagnosis and treatment of infections. An infectious diseases specialist's practice consists of managing nosocomial ( healthcare-acquired ) infections or community-acquired infections. [ 1 ]
Transmission-based precautions are infection-control precautions in health care, in addition to the so-called "standard precautions". They are the latest routine infection prevention and control practices applied for patients who are known or suspected to be infected or colonized with infectious agents, including certain epidemiologically important pathogens, which require additional control ...
A subclinical infection—sometimes called a preinfection or inapparent infection—is an infection by a pathogen that causes few or no signs or symptoms of infection in the host. [1] Subclinical infections can occur in both humans and animals. [ 2 ]