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Escherichia coli (E. Coli) is the predominant microbial trigger of UTIs, accounting for 75% to 95% of reported cases. Other pathogens such as Proteus mirabilis, Klebsiella pneumoniae, and Staphylococcus saprophyticus can also cause UTIs. [2] [3] The use of antimicrobial therapy to treat UTIs started in the 20th century.
Uropathogenic E. coli from the gut is the cause of 80–85% of community-acquired urinary tract infections, [31] with Staphylococcus saprophyticus being the cause in 5–10%. [4] Rarely they may be due to viral or fungal infections. [ 32 ]
Nitrofurantoin, sold under the brand name Macrobid among others, is an antibacterial medication of the nitrofuran class used to treat urinary tract infections (UTIs), although it is not as effective for kidney infections. [16] It is taken by mouth. [16] Common side effects include nausea, loss of appetite, diarrhea, and headaches. [16]
A 2023 study that got a lot of buzz estimated that E.coli-contaminated meat leads to nearly half a million UTIs in the U.S. each year, making it one of the most common causes of UTIs.
Bacteriuria accompanied by symptoms is a urinary tract infection while that without is known as asymptomatic bacteriuria. [1] [2] Diagnosis is by urinalysis or urine culture. [3] Escherichia coli is the most common bacterium found. [1] People without symptoms should generally not be tested for the condition. [3] Differential diagnosis include ...
Enteroaggregative Escherichia coli (EAEC or EAggEC) are a pathotype of Escherichia coli which cause acute and chronic diarrhea in both the developed and developing world. [1] [2] They may also cause urinary tract infections. [2] EAEC are defined by their "stacked-brick" pattern of adhesion to the human laryngeal epithelial cell line HEp-2. [3]