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Takayasu's arteritis (TA), also known as aortic arch syndrome, nonspecific aortoarteritis, and pulseless disease, [2] is a form of large vessel granulomatous vasculitis [3] with massive intimal fibrosis and vascular narrowing, most commonly affecting young or middle-aged women of Asian descent, though anyone can be affected.
The aortic arch is the connection between the ascending and descending aorta, and its central part is formed by the left 4th aortic arch during early development. [12] The ductus arteriosus connects to the lower part of the arch in foetal life. This allows blood from the right ventricle to mostly bypass the pulmonary vessels as they develop.
The first and second arches disappear early. A remnant of the 1st arch forms part of the maxillary artery, [3] a branch of the external carotid artery. The ventral end of the second develops into the ascending pharyngeal artery, and its dorsal end gives origin to the stapedial artery, [3] a vessel which typically atrophies in humans [4] [5] but persists in some mammals.
Heart disease symptoms depend on the type and severity of the heart disease but generally may include: ... Aortic aneurysms are a serious type of aneurysm because they form in the aorta, the main ...
An aortic aneurysm often doesn’t cause symptoms, but it can lead to severe, sudden bleeding from a ruptured aneurysm. A ruptured aneurysm has a high risk of death. If symptoms of an aortic ...
The aortic wall dilatation at the commissural level causes the cusps to effectively shorten and prevent them from converging during systole, which results in aortic valve incompetence. The arch is typically spared from the aneurysmal process, though it may involve the entire ascending aorta. The ectatic aorta may experience dissections.
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