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Symptoms including blurring or loss of vision, headache, and (rarely) stroke or coma are due to the effects of the IgM paraprotein, which may cause autoimmune phenomena or cryoglobulinemia. Other symptoms of Waldenström macroglobulinemia are due to hyperviscosity syndrome, which is present in 6–20% of patients.
Waldenström macroglobulinemia is an uncommon cancer of the blood cells that is distinguished by the proliferation of abnormal white blood cells within the bone marrow. These aberrant cells resemble both B cells, which are white blood cells, also known as lymphocytes , and plasma cells , which are B cells that went through a secondary type of ...
Waldenström first described, in 1944, patients with a disease that has subsequently been named for him, Waldenström's macroglobulinemia, a "hyperviscosity syndrome" in which symptoms are caused by abnormal lymphocytes that prevent normal bone marrow function, which causes anemia and hepatosplenomegaly, and secrete large immunoglobulins ...
The Mayo Clinic diet was created by weight management practitioners at the Mayo Clinic and was designed as a lifestyle change program to promote gradual and sustained weight loss, says Melissa ...
What is Waldenström's macroglobulinemia? ... Other symptoms include loss of appetite, fever, weight loss and the sensation of pins and needles in the feet and legs, known as neuropathy. Lesser ...
Bing–Neel syndrome (BNS) is an extremely rare neurologic complication of Waldenström macroglobulinemia (WM), which is a chronic lymphoproliferative disorder. [1] There's no clear definition of BNS but what is known so far is that unlike WM, It involves the central nervous system (CNS), infiltrated by differentiated malignant B cells and by having hyperglobulinemia. [2]
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Detection of Bence Jones protein may be suggestive of multiple myeloma, [2] or Waldenström's macroglobulinemia. [ citation needed ] Bence Jones proteins are particularly diagnostic of multiple myeloma in the context of target organ manifestations such as kidney failure , lytic (or "punched out") bone lesions, anemia , or large numbers of ...
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