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Syphilis (/ ˈ s ɪ f ə l ɪ s /) is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum. [1] The signs and symptoms depend on the stage it presents: primary, secondary, latent or tertiary.
Some infants with congenital syphilis have symptoms at birth, but many develop symptoms later. Symptoms may include rash, fever, large liver and spleen, and skeletal abnormalities. [17] Newborns will typically not develop a primary syphilitic chancre but may present with signs of secondary syphilis (i.e. generalized body rash).
About 500 million have either syphilis, gonorrhea, chlamydia or trichomoniasis. [1] At least an additional 530 million have genital herpes, and 290 million women have human papillomavirus. [1] Historical documentation of STIs in antiquity dates back to at least the Ebers Papyrus (c. 1550 BCE) and the Hebrew Bible/Old Testament (8th/7th C. BCE ...
But syphilis isn’t just on the rise in Houston: Data from the Centers for Disease Control and Prevention (CDC) published in April found that, while syphilis cases made up a fraction of sexually ...
Congenital syphilis cases have more than tripled in recent years, with over 3,700 cases reported in 2022, according to the CDC. This is the highest number since 1994.
Scientists have also debated if neurosyphilis is the result the bacterial invasion of the CNS or the immune system responding to bacteria in the CNS. [3] In primary or secondary syphilis, invasion of the protective membrane of the brain called the meninges may result in lymphocytic and plasma cell infiltration of perivascular spaces.