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This inflammation can cause pain and stiffness [5] and is one of the most common causes of ankle problems. [ 7 ] In many types of arthritis, progressive joint degeneration in the joint occurs and smooth "buffered" cartilage is gradually lost, causing the bones rub against each other and wear, as well as the soft joint tissue.
The rehabilitation is often long and demanding. The main reason is that it takes a long time for the cartilage cells to adapt and mature into repair tissue. Cartilage is a slow adapting substance. Where a muscle takes approximately 35 weeks to fully adapt itself, cartilage only undergoes 75% adaptation in 2 years.
Autologous chondrocyte implantation (ACI, ATC code M09AX02 ()) is a biomedical treatment that repairs damages in articular cartilage.ACI provides pain relief while at the same time slowing down the progression or considerably delaying partial or total joint replacement (knee replacement) surgery.
Though articular cartilage damage is not life-threatening, it does strongly affect one's quality of life. Articular cartilage damage is often the cause of severe pain, knee swelling, substantial reduction in mobility and severe restrictions to one's activities. Over the last decades, however, research has focused on regenerating damaged joints.
It is designed to address ankle instability. More importantly, it is primarily used to repair the anterior talofibular ligament (ATFL) in the ankle. It is thought that the majority of patients regain most function in their ankles. The recovery time for the procedure varies according to the patient but usually takes a minimum of 3–6 months. [1]
This causes new cartilage to develop from a so-called super-clot. The surgery is quick (typically lasting between 30 and 90 minutes), minimally invasive, and can have a significantly shorter recovery time than an arthroplasty (knee replacement). Chronic articular cartilage defects do not heal spontaneously. [1]
Significant recovery generally occurs within four months while completely recovery usually takes up to one year. [20] Ankle fractures are common, occurring in over 1.8 per 1000 adults and 1 per 1000 children per year. [21] [22] In North America this figure increases to more than 14 in ever 10,000 patients admitted to the Emergency Room. [23]
Ankle replacement, or ankle arthroplasty, is a surgical procedure to replace the damaged articular surfaces of the human ankle joint with prosthetic components. This procedure is becoming the treatment of choice for patients requiring arthroplasty, replacing the conventional use of arthrodesis , i.e. fusion of the bones.