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Monosaccharide color code in the Symbol Nomenclature For Glycans (SNFG) The Symbol Nomenclature For Glycans (SNFG) [1] is a community-curated standard for the depiction of simple monosaccharides and complex carbohydrates using various colored-coded, geometric shapes, along with defined text additions. [2] [3] It is hosted by the National Center ...
Glycan nomenclature is the systematic naming of glycans, which are carbohydrate-based polymers made by all living organisms. In general glycans can be represented in (i) text formats, these include commonly used CarbBank, IUPAC name, and several other types; and (ii) symbol formats, these are consisting of Symbol Nomenclature For Glycans and Oxford Notations.
N-Linked glycans are attached in the endoplasmic reticulum to the nitrogen (N) in the side chain of asparagine (Asn) in the sequon.The sequon is an Asn-X-Ser or Asn-X-Thr sequence, where X is any amino acid except proline and the glycan may be composed of N-acetylgalactosamine, galactose, neuraminic acid, N-acetylglucosamine, fucose, mannose, and other monosaccharides.
In molecular biology and biochemistry, glycoconjugates are the classification family for carbohydrates – referred to as glycans – which are covalently linked with chemical species such as proteins, peptides, lipids, and other compounds. [1] Glycoconjugates are formed in processes termed glycosylation.
In contrast, the oligosaccharides themselves are often referred to as paucimannosidic, low mannose, and truncated glycans or other less conventional nomenclature. [4] A simple shorthand nomenclature has been proposed as a convenient way to name the individual paucimannosidic glycan structures, e.g. M3F denotes Man 3 GlcNAc 2 Fuc 1. [6] [7] [8] [9]
Vendor Glycoconjugates, Glycan Recognizing Proteins; The Functional Glycomics Gateway. monthly updated web resource, a collaboration of Nature and the Consortium for Functional Glycomics. Carolyn Bertozzi's Seminar: "Chemical Glycobiology" Emanual Maverakis; et al. "Glycans in the immune system and The Altered Glycan Theory of Autoimmunity" (PDF).
An oligosaccharide has both a reducing and a non-reducing end. The reducing end of an oligosaccharide is the monosaccharide residue with hemiacetal functionality, thereby capable of reducing the Tollens’ reagent, while the non-reducing end is the monosaccharide residue in acetal form, thus incapable of reducing the Tollens’ reagent. [2]
Nomenclature of Inorganic Chemistry, by chemists commonly referred to as the Red Book, is a collection of recommendations on inorganic chemical nomenclature. It is published at irregular intervals by the International Union of Pure and Applied Chemistry (IUPAC). The last full edition was published in 2005, [8] in both paper and electronic versions.