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  2. Nonsteroidal anti-inflammatory drug - Wikipedia

    en.wikipedia.org/wiki/Nonsteroidal_anti...

    Kidney failure is especially a risk if the patient is also concomitantly taking an ACE inhibitor (which removes angiotensin II's vasoconstriction of the efferent arteriole) and a diuretic (which drops plasma volume, and thereby RPF)—the so-called "triple whammy" effect. [82] In rarer instances NSAIDs may also cause more severe kidney ...

  3. Sulindac - Wikipedia

    en.wikipedia.org/wiki/Sulindac

    Sulindac is much more likely than other NSAIDs to cause damage to the liver or pancreas, though it is less likely to cause kidney damage than other NSAIDs. Sulindac seems to have a property, independent of COX-inhibition, of reducing the growth of polyps and precancerous lesions in the colon, especially in association with familial adenomatous ...

  4. Analgesic nephropathy - Wikipedia

    en.wikipedia.org/wiki/Analgesic_nephropathy

    NSAIDs caused no adverse effects on renal function in healthy dogs subjected to anesthesia. [11] [12] [13] Most healthy kidneys contain enough physiologic reserve to compensate for this NSAID-induced decrease in blood flow. However, those subjected to additional injury from phenacetin or paracetamol may progress to analgesic nephropathy.

  5. Diclofenac - Wikipedia

    en.wikipedia.org/wiki/Diclofenac

    Diclofenac, sold under the brand name Voltaren among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory diseases such as gout. [6] [9] It can be taken orally (swallowed by mouth), inserted rectally as a suppository, injected intramuscularly, injected intravenously, applied to the skin topically, or through eye drops.

  6. Diflunisal - Wikipedia

    en.wikipedia.org/wiki/Diflunisal

    In October 2020, the U.S. Food and Drug Administration (FDA) required the drug label to be updated for all nonsteroidal anti-inflammatory medications to describe the risk of kidney problems in unborn babies that result in low amniotic fluid. [15] [16] They recommend avoiding NSAIDs in pregnant women at 20 weeks or later in pregnancy. [15] [16]

  7. Meloxicam - Wikipedia

    en.wikipedia.org/wiki/Meloxicam

    Common side effects include abdominal pain, dizziness, swelling, headache, and a rash. [11] Serious side effects may include heart disease, stroke, kidney problems, and stomach ulcers. [11] Use is not recommended in the third trimester of pregnancy. [11] It blocks cyclooxygenase-2 (COX-2) more than it blocks cyclooxygenase-1 (COX-1). [11]

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