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Sequential analysis also has a connection to the problem of gambler's ruin that has been studied by, among others, Huygens in 1657. [12]Step detection is the process of finding abrupt changes in the mean level of a time series or signal.
Sample size determination or estimation is the act of choosing the number of observations or replicates to include in a statistical sample. The sample size is an important feature of any empirical study in which the goal is to make inferences about a population from a sample.
The use of a sequence of experiments, where the design of each may depend on the results of previous experiments, including the possible decision to stop experimenting, is within the scope of sequential analysis, a field that was pioneered [12] by Abraham Wald in the context of sequential tests of statistical hypotheses. [13]
This is sufficient to determine which explanatory variables affect the response variable(s) of interest. Once it is suspected that only significant explanatory variables are left, then a more complicated design, such as a central composite design can be implemented to estimate a second-degree polynomial model, which is still only an ...
Sequential estimation is the core of many well known applications, such as the Viterbi decoder, convolutional codes, video compression or target tracking. Due to its state space representation, which is in most cases motivated by physical laws of motion, there is a direct link to control applications, which led to the use of the Kalman filter ...
The design matrix has dimension n-by-p, where n is the number of samples observed, and p is the number of variables measured in all samples. [4] [5]In this representation different rows typically represent different repetitions of an experiment, while columns represent different types of data (say, the results from particular probes).
For example, exactly identified models produce finite sample estimators with no moments, so the estimator can be said to be neither biased nor unbiased, the nominal size of test statistics may be substantially distorted, and the estimates may commonly be far away from the true value of the parameter.
The explanatory variable is the diet pill and the response variable is the amount of weight loss. Although the sex of the patient is not the main focus of the experiment—the effect of the drug is—it is possible that the sex of the individual will affect the amount of weight lost.