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This is a type of targeted therapy which uses the physical, chemical and biological properties of the radiopharmaceutical to target areas of the body for radiation treatment. [3] The related diagnostic modality of nuclear medicine employs the same principles but uses different types or quantities of radiopharmaceuticals in order to image or ...
A radioactive substance can be combined with a relevant peptide (or its analogue) so that it preferentially binds to the tumour. [2] [3] With a gamma emitter as the radionuclide, the technique can be used for imaging with a gamma camera or PET scanner to locate tumours. When paired with alpha or beta emitters, therapy can be achieved, as in ...
They include 30 nuclides with measured half-lives longer than the estimated age of the universe (13.8 billion years [17]), and another four nuclides with half-lives long enough (> 100 million years) that they are radioactive primordial nuclides, and may be detected on Earth, having survived from their presence in interstellar dust since before ...
Nuclear medicine (nuclear radiology, nucleology), [1] [2] is a medical specialty involving the application of radioactive substances in the diagnosis and treatment of disease. Nuclear imaging is, in a sense, radiology done inside out , because it records radiation emitted from within the body rather than radiation that is transmitted through ...
Targeted alpha-particle therapy (or TAT) is an in-development method of targeted radionuclide therapy of various cancers. It employs radioactive substances which undergo alpha decay to treat diseased tissue at close proximity. [1] It has the potential to provide highly targeted treatment, especially to microscopic tumour cells.
Some radionuclides, such as cobalt-60 and iridium-192, are made by the neutron irradiation of normal non-radioactive cobalt and iridium metal in a nuclear reactor, creating radioactive nuclides of these elements which contain extra neutrons, compared to the original stable nuclides. In addition to their uses in radiography, both cobalt-60 (60 Co
Radiopharmacology is radiochemistry applied to medicine and thus the pharmacology of radiopharmaceuticals (medicinal radiocompounds, that is, pharmaceutical drugs that are radioactive). Radiopharmaceuticals are used in the field of nuclear medicine as radioactive tracers in medical imaging and in therapy for many diseases (for example ...
The field of radiation therapy began to grow in the early 1900s largely due to the groundbreaking work of Nobel Prize–winning scientist Marie Curie (1867–1934), who discovered the radioactive elements polonium and radium in 1898. This began a new era in medical treatment and research. [119]