Ad
related to: clindamycin use in necrotizing fasciitis treatment
Search results
Results From The WOW.Com Content Network
In cases of streptococcal toxic shock syndrome, treatment consists of penicillin and clindamycin, given with intravenous immunoglobulin. [ 27 ] For toxic shock syndrome and necrotizing fasciitis, high-dose penicillin and clindamycin are used.
Necrotizing fasciitis (NF), also known as flesh-eating disease, is an infection that kills the body's soft tissue. [3] It is a serious disease that begins and spreads quickly. [ 3 ] Symptoms include red or purple or black skin, swelling, severe pain, fever , and vomiting. [ 3 ]
S. pyogenes invasion and multiplication in the fascia beneath the skin can lead to necrotizing fasciitis, a life-threatening surgical emergency. [35] [36] The bacterium is also an important cause of infection in newborns, who are susceptible to some forms of the infection that are rarely seen in adults, including meningitis. [37] [38]
Clindamycin is a lincosamide antibiotic medication used for the treatment of a number of bacterial infections, including osteomyelitis (bone) or joint infections, pelvic inflammatory disease, strep throat, pneumonia, acute otitis media (middle ear infections), and endocarditis. [5]
The Eagle effect, Eagle phenomenon, or paradoxical zone phenomenon, named after Harry Eagle who first described it, originally referred to the paradoxically reduced antibacterial effect of penicillin at high doses, [1] [2] though recent usage generally refers to the relative lack of efficacy of beta lactam antibacterial drugs on infections having large numbers of bacteria. [3]
The clinical presentation among invasive disease is also dominated by skin and soft tissue infections, including a small subset of patients presenting with severe necrotizing fasciitis. [1] [2] Moreover, it is an important cause of bone and joint infections, and this disease manifestation is reported to be increasing. [12]
Toxic shock syndrome (TSS) is a condition caused by bacterial toxins. [1] Symptoms may include fever, rash, skin peeling, and low blood pressure. [1] There may also be symptoms related to the specific underlying infection such as mastitis, osteomyelitis, necrotising fasciitis, or pneumonia.
Necrotizing fasciitis [33] Poststreptococcal glomerulonephritis [48] Penicillin G [33] [48] or V [48] Macrolide, e.g. clarithromycin [33] or erythromycin [48] in penicillin allergy; Drainage and debridement for necrotizing fasciitis [33] No vaccine [33] Rapid antibiotic treatment helps prevent rheumatic fever [33] viridans: Oral flora, [48 ...