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Candida albicans is an opportunistic pathogenic yeast [5] that is a common member of the human gut flora. It can also survive outside the human body. It can also survive outside the human body. [ 6 ] [ 7 ] It is detected in the gastrointestinal tract and mouth in 40–60% of healthy adults.
Candida tropicalis is a species of yeast in the genus Candida. It is a common pathogen in neutropenic hosts, in whom it may spread through the bloodstream to peripheral organs. [ 1 ] For invasive disease, treatments include amphotericin B , echinocandins , or extended-spectrum triazole antifungals .
Her research considers Candida albicans (C. albicans), a fungal pathogen that can causes several diseases. [4] C. albicans typically colonises the gastrointestinal tract of humans without causing any problems, but when the host organism becomes immunocompromised the pathogen produces invasive lesions that are associated with candidiasis. [5]
Candida is located on most mucosal surfaces and mainly the gastrointestinal tract, along with the skin. [3] Candida albicans is one of the most commonly isolated species and can cause infections (candidiasis or thrush) in humans and other animals. In winemaking, some species of Candida can potentially spoil wines. [4]
The cytolytic peptide Candidalysin is produced during hyphal formation by Candida albicans; it is an example of a virulence factor from a fungus. Other virulence factors include factors required for biofilm formation (e.g. sortases) and integrins (e.g. beta-1 and 3). [7]
A biofilm is a syntrophic community of microorganisms in which cells stick to each other and often also to a surface. [2] [3] These adherent cells become embedded within a slimy extracellular matrix that is composed of extracellular polymeric substances (EPSs).
Candida dubliniensis is a fungal opportunistic pathogen originally isolated from AIDS patients. It is also occasionally isolated from immunocompetent individuals. It is of the genus Candida , very closely related to Candida albicans but forming a distinct phylogenetic cluster in DNA fingerprinting .
Candida albicans is a species of fungus that is associated with oral thrush and gastrointestinal infection. [22] [23] Coccidioides immitis is a fungus known for causing coccidioidomycosis, more commonly known as Valley Fever. [24]