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For example, if the primary tumor grade was 2 and the secondary tumor grade was 3 but some cells were found to be grade 4, the Gleason score would be 2+4=6. This is a slight change from the pre-2005 Gleason system where the second number was the secondary grade (i.e., the grade of the second-most common cell line pattern). [4]
[9] [10] [11] For prostate cancer, grade group information and prostate-specific antigen levels are used in conjunction with TNM status to group cases into four overall stages. [10] [citation needed] Grade Group 1 = Gleason 6 (or less) Grade Group 2 = Gleason 3+4=7; Grade Group 3 = Gleason 4+3=7; Grade Group 4 = Gleason 8; Grade Group 5 ...
[note 1] Gleason scores are commonly grouped into "Gleason grade groups", which predict disease prognosis: a Gleason score of 6 is Gleason grade group 1 (best prognosis). A score of 7 (with Gleason scores 4 + 3, or Gleason scores 3 + 4, with the most prominent listed first) can be grade group 2 or 3; it is grade group 2 if the less severe ...
[4] 5) Clarify “risk” based on Gleason scale. Add: "A Gleason score of 6 is considered low risk and 3+4=7 is intermediate risk. Both 4+3=7 and 8-10 are considered high risk." [5] 6) Make Gleason Grade consistent throughout. i.e., In the article, it mentions G score, cancer grade, histologic grade, etc. We suggest replacing those with ...
3. Another typical Gleason score might be 7 (3+ 4), where the primary pattern has a Gleason grade of 3 and the secondary pattern has a grade of 4. 4. Finally, the highest possible Gleason score is 10 (5 + 5), when the primary and secondary patterns both have the most disordered Gleason grades of 5.
Urus:V8 4.0-litre twin turbo Urus SE:V8 4.0-litre twin turbo with electric motor [2] 305 km/h (190 mph) Revuelto: 2023–present Coupe: In production V12 6.5-litre with 3 electric motors 350 km/h (220 mph) Temerario: 2025 (to commence) Coupe: (to commence) V8 4.0-litre twin turbo with 3 electric motors 343 km/h (213 mph) [3]
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