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Trazodone, sold under many brand names, [1] is an antidepressant medication [20] used to treat major depressive disorder, anxiety disorders, and insomnia. [20] It is a phenylpiperazine compound of the serotonin antagonist and reuptake inhibitor (SARI) class.
[43] [44] Prolonged-release melatonin is safe with long-term use of up to 12 months. [11] Although not recommended for long-term use beyond this, [ 45 ] low-dose melatonin is generally safer, and a better alternative, than many prescription and over-the-counter sleep aids if a sleeping medication must be used for an extended period of time.
Chemical structure of the serotonin antagonist and reuptake inhibitor trazodone. Serotonin antagonist and reuptake inhibitors (SARIs) are a class of drugs used mainly as antidepressants, but also as anxiolytics and hypnotics.
From scaling back their portions of the best dog food to ensuring they get enough exercise each day, here are some simple things you can do to help your dog lose weight… 32 things you can do to ...
He adds that both can go well together. When insomnia is the key issue, he typically begins with a sustained-release of 10 mg of melatonin, adding other treatments as needed.
Discontinuation symptoms can be managed by tapering, a gradual reduction in dosage over a period of days, weeks or sometimes months to minimize or prevent withdrawal symptoms. [ 38 ] MAOIs, as with most antidepressant medication, may not alter the course of the disorder in a significant, permanent way, so it is possible that discontinuation can ...