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Hypotonia is a lack of resistance to passive movement, whereas muscle weakness results in impaired active movement. Central hypotonia originates from the central nervous system, while peripheral hypotonia is related to problems within the spinal cord, peripheral nerves and/or skeletal muscles. [2]
Central and peripheral refer to the distance towards and away from the centre of something. [33] That might be an organ, a region in the body, or an anatomical structure. For example, the central nervous system and the peripheral nervous systems. Central (from Latin centralis) describes something close to the centre. [33]
Image of the human brain showing sulci, gyri, and fundi shown in a Coronal section. Specific terms are used to represent the gross anatomy of the brain: A gyrus is an outward folding of the brain, for example the precentral gyrus. A sulcus is an inward fold, or valley in the brain's surface - for example the central sulcus. Additional terms ...
For example, a person can be high tone with normal to poor flexibility in most areas, but be able to put the palms of the hands on the floor with straight knees due to hypermobile sacroiliac joints. [citation needed] It is important to assess several areas before deciding if a person has high, low, or normal muscle tone. A fairly reliable ...
Primary symptoms of the disease are developmental delay, progressive intellectual disability, hypotonia (low muscle tone), spasticity (stiffness of the limbs) possibly leading to quadriplegia, and progressive dementia. Seizures may include epilepsia partialis continua, a type of seizure that consists of repeated myoclonic (muscle) jerks.
Hypertonia is a term sometimes used synonymously with spasticity and rigidity in the literature surrounding damage to the central nervous system, namely upper motor neuron lesions. [1] Impaired ability of damaged motor neurons to regulate descending pathways gives rise to disordered spinal reflexes , increased excitability of muscle spindles ...
Sensory ataxia can be a manifestation of sensory large fiber peripheral neuropathies and conditions causing dysfunction of the dorsal columns of the spinal cord due to a variety of disorders: infectious, auto-immune, metabolic, toxic, vascular and hereditary diseases.
Peripheral regulation therefore depends on the localized metabolic chemical conditions of the local muscle affected, whereas the central model of muscle fatigue is an integrated mechanism that works to preserve the integrity of the system by initiating muscle fatigue through muscle derecruitment, based on collective feedback from the periphery ...